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Tissue Engineering

Matrix composition has an important role in embryonic stem cell development

Published in Blood Weekly, October 20th, 2005

Matrix composition has an important role in embryonic stem cell development.

"The use of embryonic stem (ES) cells as unlimited cell source in tissue engineering has ignited the hope of regenerating any kind of tissue in vitro. However, the role of the material in control and guidance of their development and commitment into complex and viable 3-dimensional (3D) tissues is still poorly understood," scientists in Italy report.

"In this work, we investigate the role of material composition and structure on promoting ES cells growth and differentiation, by culturing mouse ES cell-derived embryoid bodies (EBs) in various semi-interpenetrating polymer...

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