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Oncology

Accelerated lymphangiogenesis in malignant lymphoma may be linked to VEGF-A and VEGF-C

Published in Blood Weekly, October 27th, 2005

Accelerated lymphangiogenesis in malignant lymphoma may be linked to vascular endothelial growth factor (VEGF)-A and VEGF-C.

"There is little information regarding the lymphangiogenesis of malignant lymphoma. In this study, we evaluated the lymphangiogenesis and angiogenesis in 44 lymph nodes of 39 malignant lymphomas and five non-reactive normal lymph nodes, based on the lymphatic vessel density (LVD) and microvessel density (MVD) calculated by the computer-assisted assessment of vessel density," researchers in Japan report.

"The LVD of malignant lymphomas was significantly higher than that of non-reactive normal lymph nodes, irrespective of...

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