Pharmacology
Clobazam and major metabolite detected in human plasma by a rapid HPLC method
Published in Blood Weekly, October 27th, 2005
"A rapid and specific HPLC method has been developed and validated for simultaneous determination of clobazam, the anticonvulsant agent, and its major metabolite in human plasma. The sample preparation was a liquid-liquid extraction with toluene yielding almost near 100% recoveries of two compounds," scientists in Iran report.
"Chromatographic separation was achieved with a Chromolith Performance RP-18e 100 mmx4.6 mm column, using a mixture of a phosphate buffer (pH 3.5; 10mM)-acetonitrile (70:30, v/v), in isocratic mode at 2ml/min at a detection wave-length of...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Blood Weekly
Source: Blood Weekly (2005-10-27)
More Articles from Blood Weekly
- Hemophilia
U.S. FDA approves room temperature storage of Helixate FS - Stem Cell Research
Hematopoietic stem cells age-related changes favor myelopoiesis - Stem Cell Transplantation
Donor infusions result in residual/relapsed lymphoid malignancy remission - Stem Cell Transplantation
MSC transplantation and hydroxyapatite ceramics treat severe osteochondral damage - Acute Myeloid Leukemia
EMEA grants orphan drug designation to Troxatyl for acute myeloid leukemia - Adverse Drug Reaction
Drugs raise mitochondrial toxicity risk in HIV/hepatitis C-coinfected patients - More from this issue of Blood Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
