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Stem Cell Transplantation

G-CSF therapy response predicts better survival in poor graft function patients

Published in Blood Weekly, October 27th, 2005

Hematological response after 3 days of granulocyte colony-stimulating factor therapy predicts better survival in patients with poor graft function following stem cell transplantation.

According to a study from France, "Poor graft function (PGF) is a frequent cause of morbidity after allogeneic hematopoietic stem cell transplantation (allo-HSCT).

"To study the value of granulocyte colony-stimulating factor (G-CSF) in PGF, we retrospectively analyzed 81 episodes of PGF in 66 patients transplanted from 01/94 to 01/99 from an HLA-identical sibling (n=45) or an unrelated (n=21) donor."

"Median age was 29 years, 55 patients had...

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