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Abdominal Surgery

Ischemic preconditioning augments intestinal microvascular perfusion and oxygenation

Published in Blood Weekly, November 3rd, 2005

Ischemic preconditioning (IPC) augments intestinal microvascular perfusion and oxygenation in a rat model.

"Ischemia-reperfusion (IR) injury of the intestine occurs commonly during abdominal surgery," while IPC "provides a way of protecting the organ from damage inflicted by IR," surgeons in England explained.

I.H. Mallick and colleagues at University College London conducted a study "to evaluate the beneficial effect of IPC, focusing on the intestinal microcirculation and oxygenation in intestinal IR injury."

"Rats were allocated to three groups. Animals in the IR and IPC groups underwent 30 min of intestinal ischemia followed by...

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