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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . November 10th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Blood Banking - MAIRA assay appears suitable for measurement of red blood cell markers during storage

Blood Safety - Improved blood safety measures can increase platelet availability

Diagnostics - Flow cytometry method quantifies isotype-specific ABO blood group antibodies

Stem Cell Proliferation - Low power laser radiation stimulates stem cell proliferation rate during tissue regeneration

Stem Cell Transplantation - Home care during pancytopenic phase after ASCT improves long-term survival

Anesthesiology - Near infrared laser device can measure brain oxygen levels during surgery

Angiology - Nitroxyl is an inhibitor of human platelet function

Cancer Risk Factors - Occupation and hobbies linked to acute leukemia in adults

Cancer Risk Factors - Patients with rheumatoid arthritis linked to increased risk of cancer

Cancer Therapy - Helenalin found to be potent inhibitor of human telomerase

Candidemia - Prior sepsis, current GI pathology are risk factors for neonatal ICU patients

Cardiology - Transduced myoblasts prompt endothelial cells to form vessel-like structures

Cardiovascular Disease - Nocturnal hemodialysis is associated with restoration of EPC biology in ESRD

Cardiovascular Research - Heparin coating improves biocompatibility and reduces area of platelet mass

Clinical Trials - Clearance granted for phase II trial of treatment for acute graft vs. host disease

Coagulation - Human megakaryocytes process plasma factor V into alpha-granules

Collaborations - Exclusive license signed to market new stem cell service

Complementary & Alternative Medicine - Indirubin promotes neutrophilic differentiation of human myelocytic leukemia cells

Complementary & Alternative Medicine - Kaempferol exhibited different effects in T cell signaling cascade

Cord Blood - Company provides master file to U.S. FDA for system to harvest mononuclear cells

Dermatology - Scleroderma medication receives orphan medication designation in Europe

Diagnostics - Companies team up to provide hs-CRP test for clinical trial recruitment and screenings

Diagnostics - HCV-RNA transcription-mediated amplification detects infection in hemodialysis patients

Drug Development - Orphan drug status approved for sickle cell medicine in European Union

Drug Development - Video spotlights company's drug candidates to treat multiple myeloma, leukemia

Finance - Endovascular device company reports Q3 2005 net sales up 70% to $33.5 million

Finance - PolyHeme developer reports loss of $5.8 million for first quarter 2006

Finance - Tissue engineering company announces $3.3 million private placement

Fitness & Wellness - Caution suggested when using a sauna

Gastroenterology - Low blood glucose levels may complicate gastric bypass surgery, study shows

HIV/AIDS Diagnostics - Molecular tests company investigating collaboration for testing blood samples

Heart Surgery - Hydroxyethyl starch 130/0.4 suitable as alternative to modified fluid gelatin for volume expansion

Hematology - Patient host factors prevent GB virus C, hepatitis, and HIV infection in exposed hemophiliacs

Hemodialysis - Hydroperoxides are accurate markers of acute oxidative injury, unlike malondialdehyde

Hepatitis C Virus - Tattooing practices foster hepatitis C transmission on the Texas-Mexico border

Hodgkin Lymphoma - Doctors can halve the radiation dose and still retain high survival in Hodgkin lymphoma

Hypertension - Beta blockers should not remain first treatment for high blood pressure

Hypertension - Deep brain stimulation can lower blood pressure

Hypertension - Group urges doctors to go beyond blood pressure numbers in defining hypertension

Hypertension - New genetic link to high blood pressure described

Hypoglycemia - Novel ion-trap assay detects and measures eight sulfonylureas in plasma

Imaging - Four-color confocal fluorescence optimizes imaging of chondrocyte cytoskeleton

Infections - Lipopolysaccharide interaction with thiol may be the basis of oxidative stress in blood platelets

Ischemia - Neutrophil generated HOCl causes oxidative stress during reperfusion injury phase

Joint Replacement - Serum IL-6 is an accurate diagnostic marker of periprosthetic infection

Leukemia - HOXA9 expression may increase with age in human hemopoietic cells

Macular Degeneration - Biopharma company announces research on vascular disrupting agent

Nanotechnology - Nanophase ceramics increase osteoblast function

Nanotechnology - Researchers report that carbon nanoparticles stimulate blood clotting

Neoplasms - Plasma cell neoplasms reviewed

Neuroscience - Dr. Peter Vajkoczy presents latest data on Bowman Perfusion Monitoring System

Neuroscience - Nonsynaptic GABAergic signaling exists between neuroblasts and GFAP-expressing cells

Ophthalmology - Ophthalmologist to examine ancient Chilean mummy eyes

Patent Foramen Ovale - New device closes heart defect, preventing unfiltered blood from entering circulation

Peripheral Artery Disease - Cryoplasty effectively treats challenging peripheral artery blockages

Physiology - p47phox-dependent NADPH oxidase regulates flow-induced vascular remodeling

Progenitor Cells - Expanded endothelial progenitor cells help restore blood flow in ischemic limbs

Prognostics - Anemia used as prognostic factor in patients undergoing resection for lung cancers

Prognostics - Hematopoietic cell transplantation advised for patients with little comorbidity

Prognostics - Treatment efficacy indicated by incidence of chemotherapy-induced neutropenia

Reproductive Health - Bed rest for hypertension during pregnancy is not backed by strong evidence

Sickle Cell Disease - Inhaled nitric oxide may help sickle cell disease

Stem Cell Research - Bone marrow stem cell transplants improve heart function

Stem Cell Research - CD45+ liver subpopulation tip cells generated from bone marrow stem cells

Stem Cell Research - Confirmed survival and differentiation of ESC-derived NPCs transplanted into ischemic brain

Stem Cell Research - Decreased H19 expression associated with anticancer activity in dedifferentiated cell clones

Stem Cell Research - Extracellular signal-regulated kinase/MAPK induces neuronal markers in MSCs

Stem Cell Research - Increased TCF/beta-catenin/CBP-mediated transcription decreases neuronal differentiation

Stem Cell Research - Interleukin-4 is essential for the expression of Ym1/2 genes

Stem Cell Research - Neural stem cells partition DNA asymmetrically

Stem Cell Research - PU.1 expression necessary for maintenance of the bone marrow hematopoietic stem cell pool

Stem Cell Research - Radial cells in the spinal cord are precursors to radial glia

Stem Cell Research - Simple method yields high-density cultures of embryonic stem cells

Stem Cell Research - Stem cells produced from umbilical cord blood have embryonic characteristics

Stem Cell Transplantation - BM stem cells injected after laser photocoagulation differentiate and survive long term

Stem Cell Transplantation - BM stromal cell treatment improves neurologic recovery in autoimmune encephalomyelitis

Stem Cell Transplantation - Circulating CD34+ cells increase 10 hours after G-CSF administration

Stem Cell Transplantation - Early stem cell transplantation induced remission of chronic myeloid leukemia

Stem Cell Transplantation - Expansion capacity of mesenchymal stem cells after sex-mismatched SCT is damaged

Thrombosis - Biopharma company nears completion of preclinical data on antithrombin drug

Thyroid Surgery - LigaSure vessel sealing system provides safe and effective hemostasis

Tissue Engineering - Adrenomedullin regenerates alveoli and vasculature in elastase-induced pulmonary emphysema

Tissue Engineering - Extracellular matrix scaffold and muscle tissue used to reconstruct esophagus

Tissue Engineering - PLGA porous scaffolds are used to repair mandibular defects

Tissue Engineering - Synthetic scaffold morphology controls dermal connective tissue formation

Tissue Engineering - Tissue engineered fetal skin constructs improve healing of pediatric burns

Toxins - Heat shock response protects murine liver from endotoxemia-induced injury

Transplant Medicine - Glomerular mesangial cells share their origin with granulocytes and macrophages

Transplant Medicine - Nonprofit organ donation organization receives transplant network contract

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