Dermatology
Trichloroacetic acid peels cause a temporary impairment of skin defense system
Published in Blood Weekly, November 17th, 2005
According to recent research from Japan, "The changes in Langerhans cells (LCs) from normal human skin peeled with 40 and 60% trichloroacetic acid (TCA) or liquid nitrogen, which is known in cryosurgery as a control, were examined using monoclonal antibodies against the CD1a, HLA-DR, and Lag in order to examine the immune surveillance system."
"In the 40% TCA group, the number of CD1a-positive cells decreased gradually until day 7, whereas both HLA-DR- and Lag-positive cells decreased for 12 hours, increased until day 2 and decreased thereafter.
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Source: Blood Weekly (2005-11-17)
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