Blood Weekly
Susan Hasty, Publisher
Table of Contents . . . December 8th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Blood Safety - Empirical model investigates the determinants of a safe and sufficient blood supply
Bone Fracture - Osteoblastic cells mobilized and recruited from remote bone marrow sites for fracture healing
Stem Cell Research - Increased circulating endothelial progenitor cells associated with survival in acute lung injury
Surgery - Blood transfusions performed after musculoskeletal tumor surgery
Tissue Engineering - Collagen-modified PLGA scaffold developed for tissue engineering of the esophagus
Acute Myeloid Leukemia - Clofarabine's duration of response improves outcome for elderly AML patients
Acute Myeloid Leukemia - Gefitinib induces myeloid differentiation of acute myeloid leukemia
Acute Myeloid Leukemia - High-dose melphalan is an effective salvage therapy in acute myeloid leukemia
Acute Myeloid Leukemia - Loss of heterozygosity occurred without loss of genetic material in acute myeloid leukemia
Alcohol Use - AUDIT screen predicts patients at risk of withdrawal symptoms
Anesthesia - Preoxygenation in sitting position extends apnea tolerance compared to supine position
Tissue Engineering - Findings advance knowledge in tissue engineering research
Angiology - SGK-1 risk carriers have increased hypertension risk and high BP risk
Apoptosis - Cyclosporine A induces growth arrest or apoptosis of glioma cells
Apoptosis - Valproate increased Ara-C cytotoxicity in acute myeloblastic leukemia cells
Atherosclerosis - Studies show apo A-I Milano gene transfer cuts atherosclerotic plaque
Awards - Artificial heart developer earns Entrepreneurial Company of the Year Award
Awards - Stroke program at Washington's Swedish Medical Center receives JCAHO quality award
Tissue Engineering - Studies advance knowledge in tissue engineering research
Biomedical Engineering - Sterile organ culture system is developed for study of aortic heart valves
Blood Pressure - Exposure to high levels of noise may increases blood pressure
Cancer Gene Therapy - Gene therapy may purge leukemia cells from hematopoietic progenitor cells
Cancer Research - SCF/c-kit signaling autoactivation may contribute to carcinogenesis
Cancer Therapy - Megadose methylprednisolone did not affect bone mass any more than conventional-dose prednisolone treatments
Cancer Therapy - NF-kappa B inhibitor DHMEQ may be used to treat adult T-cell leukemia
Cancer Therapy - RNAi-mediated knockdown restores imatinib sensitivity in resistant CML cell lines
Cardiac Intervention Risk Factors - Low creatinine clearance is risk factor for major bleeding complications
Cardiology - Scientists uncover more evidence for protein's role in artery blockage
Cardiovascular Disease - Hemodialysis-unresponsive BP patients are more likely to have vascular disease
Cardiovascular Research - Amino-terminal probrain natriuretic peptide marks patients with highest sudden death risk
Chemotherapy - Combined Abl inhibitor therapy minimized drug resistance in chronic myeloid leukemia
Chemotherapy - Darbepoetin alfa therapy did not influence survival in patients with chemotherapy-induced anemia
Colon Cancer - Blood volume changes reflect tumor response to antiangiogenic therapy
Colon Cancer - E-cadherin regulates the association between beta-catenin and actinin-4
Complementary & Alternative Medicine - Cocoa reduces BP and insulin resistance, improves vasodilation in hypertensives
Coronary Artery Bypass - Researchers' findings advance coronary artery bypass research
Diabetes Control - Blood glucose levels in diabetic youth should be measured frequently
Diabetes Therapy - Exendin-4 has beneficial effects on islet transplantation
Diagnostics - Findings in diagnostics provide new insights
Diagnostics - Platelet counts and ultrasonography predict liver fibrosis in hepatitis C chronic hepatitis
Diagnostics - Semiquantitative, high-throughput microarray test detects fetal RNA in maternal plasma
Diagnostics - Visual reading of Rapicheck H-FABP test has low accuracy
Diet & Nutrition - Higher diverse diet could decrease risk for some metabolic disorders
Disease Associations - HDL cholesterol form linked to atherosclerosis in lupus patients
Disease Associations - Intramedullary capillary hemangioma associated with hydrocephalus in an infant
Disease Associations - Survivors of lymphoblastic leukemia have higher total body fat and poor lipid profile
Disease Associations - T cell antigen-recognition sites found in patients with acquired aplastic anemia
Drug Delivery - U.S. Army awards grant to investigate transdermal delivery of dengue vaccine
Drug Development - BAY 12-9566 is toxic when combined with etoposide and carboplatin
Drug Development - Inhibition of MT1-MMP interferes with diabetogenic T cell homing in the pancreas
Drug Resistance - Bcr-Abl expression levels determine resistance to imatinib mesylate in chronic myeloid leukemia
Drug Resistance - Mathematical models used to demonstrate evolutionary dynamics of chemoresistance
Finance - Pharmaceutical company raises $46 million in series B financing
Fitness & Wellness - Low fitness level is associated with increased risk of CVD mortality in diabetic men
Genetics & Genomics - Suppression subtractive hybridization identifies different regions among Yersinia pestis strains
Graft-vs-Host Disease - IL-15, but not IL-2, rapidly induces lethal xenogeneic graft-versus-host disease
HIV/AIDS Transmission - Chorioamnionitis is associated with placental transmission of HIV-1 subtype E
Hematology - Disease management company contributes to first sepsis biomarker conference
Hematology - New findings in hematology described
Hematology - VA healthcare network awards contract for hematology instrumentation services
Hepatitis B Virus - HBV vaccine effective in some chronic HBV-infected liver graft recipients
Hepatitis C Therapy - Phlebotomy is effective therapy for patients with chronic hepatitis C infections
Hepatitis C Virus - ARCHITECT Anti-HCV assay shows improved specificity for blood donor specimens
Hepatitis C Virus - Antithymocyte globulin induction therapy does not affect graft survival
Hepatitis C Virus - Blood-transmitted viral infections remain high among hemophiliacs in Tunisia
Hepatitis C Virus - Host immune responses are vital in hepatitis C virus clearance
Hepatitis C Virus - Inadequate anti-HIV CD8 T-cell responses may be a disease factor in HIV/HCV infected hemophiliacs
Hepatitis Therapy - Zinc supplementation may provide complementary therapy of chronic hepatitis C
Information Technology - Blood testing labs to employ updated data management system
Information Technology - Company releases software programs for measuring platelets and red cells
Information Technology - New web site features clinical biomarker research
Information Technology - TrackWise quality management software activated at diagnostics firm
Ischemia - Researchers provide details of new studies and findings in the area of ischemia
Legal Issues - Newborn stem cell bank announces settlement of litigation with Viacord
Leukemia - Findings advance knowledge in leukemia research
Leukemia - Pathogenesis of ATL investigated using newborn NOD/SCID/beta-2mNull mouse model
Leukocyte Adhesion Deficiency - CD18 functions critically in the osteogenesis of bone marrow stromal stem cells
Lipoproteins - Cord-blood lipoproteins may predict future health risks of infants
Liver Transplantation - Fibrosis after liver transplantation involves hepatic stellate cell activation
Marketing - Worldwide supply agreement signed for sale of thrombin processing device
Medical Devices - U.S. FDA grants 510(k) clearance to expand use of blood oxygen saturation monitor
Medical Ethics - Ethical and practical problems exist in blood sampling for research during emergencies
Mental Health - Risk of depression increases with decreasing hemoglobin levels in cancer patients
Neuropathy - Angiogenic factors exhibit a major presence in polyneuropathy syndrome
Neuroscience - Newly generated neuronal cells at sites of injury originate from the subventricular zone
Obesity Complications - Hyperviscosity in obese school children is related to subclinical atherosclerosis
Obesity Complications - Middle-aged obesity raises risk of dementia and Alzheimer disease
Obesity Complications - Obesity is linked to increased CV risk and proteinuria progression in transplant patients
Personnel - Biotech company appoints Arnon Nagler to scientific advisory board
Pharmaceutical Research - Cyclosporin A upregulates Id1 and Smad3 expression and delays skeletal muscle regeneration
Pharmaceutical Research - Pioglitazone protects obese, insulin resistant mice against arterial thrombosis
Skin Cancer - New findings in the area of skin cancer described
Spinal Cord Injury - Intraspinal application of endothelin results in focal ischemic injury of spinal gray matter
Stem Cell Research - Alternative splicing modifies components of signaling pathways important for stem cell function
Stem Cell Research - CD133-positive cells contain mesenchymal stem cells with high proliferative potential
Stem Cell Research - CD34+/CD38- cells actively migrate toward and seek contact with stroma cells
Stem Cell Research - CNS progenitor cells have stage-specific changes in gene expression during development
Stem Cell Research - Embryonic stem cell nuclei have a distinct nuclear architecture
Stem Cell Research - Endogenous neuregulins may play important roles during CNS neurogenesis
Stem Cell Research - Functional neurons developed from postnatal stem cells
Stem Cell Research - Green fluorescence protein reporter coexpressed with Sox1 protein
Stem Cell Research - High stem cell frequency in AML at diagnosis predicts high minimal residual disease and poor survival
Stem Cell Research - Homologous feeder cells support undifferentiated growth and pluripotency in embryonic stem cells
Stem Cell Research - Intron 5/6 promoter region of ship1 gene regulates expression in embryonic stem/progenitor cells
Stem Cell Research - Late-passage embryonic stem cells have one or more genomic alterations observed in cancers
Stem Cell Research - M-CSF promotes long-term engraftment of hematopoietic stem cells in the presence of cytokines
Stem Cell Research - Neural stem cell factor may control glioma cell proliferation
Stem Cell Research - Potential of adipose-derived stem cells as source of neuronal progenitor cells is examined
Stem Cell Research - Quiescent neural stem cells can self-renew for over a year and generate multiple cell types
Stem Cell Research - SCL/TAL1 expression level regulates hematopoietic stem cell self-renewal and engraftment
Stem Cell Research - Side population cells derived from adult liver generate hepatocyte-like cells
Stem Cell Research - Study reveals how OCT4, SOX2, and NANOG contribute to pluripotency and self-renewal
Stem Cell Research - Telomerase overexpression does not prevent telomere shortening in hematopoietic cells
Stem Cell Research - Wnt4-transformed embryonic stem cells differentiate into renal tubular cells
Stem Cell Transplantation - ASCT is successful in more than half of SDS patients with severe bone marrow dysfunction
Stem Cell Transplantation - HHV-6 and HHV-7 reactivations following pediatric SCT correlate with clinical symptoms
Stem Cell Transplantation - MSC transplantation could inhibit LV remodeling and improve heart function
Stem Cell Transplantation - Signaling cascades may contribute to chemotherapy-induced alterations of marrow microenvironment
Thrombosis - SNAC delivery agent developer provides update on phase III oral heparin trial design
Tissue Engineering - Apatite-promoted osteoblastic differentiation observed in 3D model system
Tissue Engineering - Chondrocytes differentially express matrix modulators during tissue engineering expansion
Tissue Engineering - Collagen and fibrin suitable substrates for 3D culture matrixes
Tissue Engineering - Data advance knowledge in tissue engineering research
Tissue Engineering - Three-dimensional perfusion culture reproducibly generates bone tissue
Transplant Medicine - Acyclovir therapy does not prevent recurrent post-transplantation hepatitis
Transplant Medicine - Composite islet-endothelial cell grafts may be able to overcome IBMIR
Transplant Medicine - Early hepatic stellate cell activation predicts hepatitis C recurrence
Type 1 Diabetes - Diabetes monocytes show raised MRP8/14 expression and reduced migration towards chemokines
Type 1 Diabetes - Interim results encouraging in animal pancreatic xenotransplantation study
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