Tissue Engineering
Valvular interstitial cell activation is mediated by TGF-beta 1 interactions with matrix molecules
Published in Blood Weekly, December 15th, 2005
"Strategies for the tissue-engineering of living cardiac valve replacements are limited by a lack of appropriate scaffold materials that both permit cell viability and actively contribute to the growth of functional tissues.
"Components of the extracellular matrix can localize and modify growth factor signals, and by doing so impart instructional stimuli for direction of cell phenotype," scientists in the United States report.
According to M.C. Cushing and colleagues at the University of Colorado, "Fibronectin, collagen 1, and...
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Source: Blood Weekly (2005-12-15)
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