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Bioartificial Liver
Pulsating flow in a hollow fiber bioartificial liver enhances cell viability
December 29th, 2005
Pulsating flow in a hollow fiber bioartificial liver enhances cell viability. According to a study from the United States, "A pulsating flow of medium was used to alleviate diffusion and transport limitations in a hollow fiber bioreactor containing a human hepatoblastoma cell line. The strategy is easy to implement but effective." "The pulsating flow is introduced by a solenoid pinch valve at the outlet of the bioreactor and regulated by a timing circuit," D.T. Nguyen and colleagues at the University of California, San Diego wrote. "In a permeability test," said the authors, "the system with pulsating flow had much less membrane...
Source: Blood Weekly (2005-12-29)
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