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Coronary Artery Bypass



Resveratrol treatment during storage reduces vein graft endothelial damage



December 29th, 2005

The use of a resveratrol-based solution can reduce endothelial damage in heart bypass vein grafts during storage.

"Endothelial injury in human saphenous vein grafts may occur during harvesting and storage, which may have an adverse effect on coronary artery bypass grafting outcome," thoracic surgeons in New York explained.

In a recent study, S. Kaplan and coauthors at Columbia University "sought to determine whether resveratrol, a natural antioxidant enriched in grape, can limit endothelial activation and reduce endothelial injury in human saphenous vein grafts."

"Human saphenous vein grafts, obtained from eight patients and...


Source: Blood Weekly (2005-12-29)

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