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Diabetes Complications
High glucose conditions increased synthesis of TSP-1 and NPY in myocardium of rat model
December 29th, 2005
High glucose conditions can induce an increased synthesis of thrombospondin-1 and neuropeptide Y in myocardium of STZ-induced rats. "Diabetic cardiomyopathy was the most dangerous diabetic complication facing diabetics, with its exact mechanisms remaining obscure. Our study was conducted to investigate the expression of thrombospondin-1 (TSP-1) and neuropeptide Y (NPY) in myocardium of streptozotocin (STZ)-induced diabetic rats," researchers in People's Republic of China report. X.M. Zhang and colleagues at Zhejiang University in Hangzhou employed "streptozotocin (STZ)-induced diabetic rats to study the alteration of the TSP-1 and NPY expression in...
Source: Blood Weekly (2005-12-29)
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