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Genetics & Genomics
Spermatogonial SCs retain euploid karyotype and androgenetic imprint during long-term culture
December 29th, 2005
Spermatogonial stem cells retain euploid karyotype and androgenetic imprint during long-term culture. According to a study from Japan, "Although stem cells are believed to divide infinitely by self-renewal division, there is little evidence that demonstrates their infinite replicative potential. Spermatogonial stem cells are the founder cell population for spermatogenesis." "Recently, in vitro culture of spermatogonial stem cells was described. Spermatogonial stem cells can be expanded in vitro in the presence of glial cell line-derived neurotrophic factor (GDNF), maintaining the capacity to produce spermatogenesis after transplantation into...
Source: Blood Weekly (2005-12-29)
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