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Stem Cell Transplantation
Ionizing radiation enhances transplanted multipotent astrocytic stem cell engraftment
December 29th, 2005
Ionizing radiation enhances transplanted multipotent astrocytic stem cell engraftment. "The subependymal zone (SEZ) is a region of persistent neurogenesis in the adult mammalian brain containing a neural stem cell (NSC) pool that continuously generates migratory neuroblasts that travel in chains through the rostral migratory stream (RMS) to the olfactory bulb (OB), where they differentiate and functionally integrate into existing neural circuitry. "NSCs can be isolated from the SEZ and cultured to generate either neurospheres (NSs) or multipotent astrocytic stem cells (MASCs), with both possessing the stem cell characteristics of multipotency and...
Source: Blood Weekly (2005-12-29)
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