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Hypertension



Intrarenal hemodynamics might impact renoprotective effect of ARB in hypertension patients



December 29th, 2005

Intrarenal hemodynamics may impact the renoprotective effect of angiotensin receptor blockade in patients with hypertension.

According to recent research from Japan, "It has been shown that both angiotensin-converting enzyme inhibitors (ACE-I) and angiotensin II type I receptor blockers (ARB) have renoprotective effects via mechanisms that are independent of blood pressure reduction. The aim of this study was to evaluate the intrarenal hemodynamic change with ARB by renal Doppler ultrasonography (RDU) and to assess the mechanism of ARB in patients with hypertension."

C. Ogata and colleagues at the National Cardiovascular Center collected data from...


Source: Blood Weekly (2005-12-29)

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