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Malaria



Host microsatellite alleles of TH01 and D5S818 are indicator of malaria susceptibility



December 29th, 2005

The host microsatellite alleles of TH01 and D5S818 are an indicator of malaria susceptibility.

"Malaria is a serious, sometimes fatal, disease caused by Plasmodium infection of human red blood cells. The host-parasite co-evolutionary processes are well understood by the association of coding variations such as G6PD, Duffy blood group receptor, HLA, and beta-globin gene variants with malaria resistance," scientists in India report.

S. Gaikwad and colleagues at the National DNA Analysis Center in West Bengal explained, "The profound genetic diversity in host is attributed to polymorphic microsatellites loci. The microsatellite alleles in...


Source: Blood Weekly (2005-12-29)

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