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Cancer Diagnostics

Methods for enumerating circulating tumor cells in carcinoma patients compared

Published in Blood Weekly, January 12th, 2006

Two methods for enumerating circulating tumor cells (CTCs) in carcinoma patients were compared.

According to recent research from Austria, "Monitoring of CTCs in blood of carcinoma patients treated with novel compounds may be a measurement of treatment effectiveness. Before it can be used clinically, a reliably method is needed to enumerate CTCs."

"We compared two methods for CTC enumeration, Onko-Quick and the CellSearch system. We drew 22.5 ml of blood into three CellSave tubes from 15 healthy donors and 61 patients with metastatic carcinoma. After pooling, 15 ml was processed with OncoQuick and 7.5 ml with CellSearch. With both methods no CTCs...

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