Published in Blood Weekly, January 12th, 2006
Study 1: An epitope derived from the cancer testis antigen HOM-TES-14/SCP1 was presented by dendritic cells to circulating CD4+ T cells.
"Because of their frequent expression in a wide spectrum of malignant tumors but not in normal tissue except testis, cancer testis antigens are promising targets. However, except for HOM-TES-14/SCP1, their expression in malignant lymphomas is rare."
"SCP1 (synaptonemal complex protein 1) has been shown to elicit antibody responses in the autologous host, but no T-cell responses against HOM-TES-114/SCP1 have been...
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Source: Blood Weekly (2006-01-12)
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