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Stem Cell Research

Nanoscale topography modulates corneal epithelial cell migration

Published in Blood Weekly, January 19th, 2006

Nanoscale topography modulates corneal epithelial cell migration.

According to recent research from the United States, "The purpose of this study was to evaluate the effect of surface topographic features that mimic the corneal epithelial basement membrane on cell migration.

"We used electron-beam and X-ray lithography and reactive ion etching to pattern silicon wafers with pitches (groove width Plus ridge width) of nano- and microscale dimensions (pitches ranged from 400 to 4000 nm)."

"Additionally," said K.A. Diehl and colleagues at the University of Wisconsin, "polyurethane patterned surfaces were created by replication molding...

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