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Disease Associations

Case of testicular tumor related to Down syndrome

Published in Blood Weekly, January 19th, 2006

Researchers reported a patient with Down syndrome developed a testicular tumor.

According to recent research from Japan, "A 33-year-old male patient with Down syndrome, who stayed in a welfare institution, visited our hospital due to left testicular enlargement. He was diagnosed as having a left testicular tumor and underwent radical inguinal orchiectomy."

"Preoperatively, serum level of beta-human chorionic gonadotrophin (beta-HCG) increased to .9 ng/mL (normal range <.2 ng/mL). For the last 2 years after orchiectomy, the serum level of beta-HCG remained normal. Histopathological examination of specimen revealed a typical seminoma," explained K....

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