Leukemia

All-trans retinoic acid and anthracycline used to treat pediatric leukemia

Published in Blood Weekly, January 19th, 2006

All-trans retinoic acid (ATRA) and anthracycline monochemotherapy were used to treat children with acute promyelocytic leukemia (APL).

Researchers in Spain conducted a study "to analyze the simultaneous combination of ATRA and anthracycline monochemotherapy for children with APL. Since November 1996, 66 children (younger than 18 years) with genetically proven APL received induction therapy with ATRA and idarubicin. Consolidation therapy consisted of three courses of anthracycline monochemotherapy."

"After November 1999, patients with intermediate and high risk of relapse received consolidation therapy with ATRA and slightly reinforced doses of...

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Source: Blood Weekly (2006-01-19)

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