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Uveal Melanoma

Circulating cancer cells create a trail for tracking uveal melanoma metastasis

Published in Blood Weekly, February 2nd, 2006

Circulating cancer cells create a trail for tracking uveal melanoma metastasis.

Researchers in Canada conducted a study "to characterize, in detail, tumor development, malignant cell dissemination, and metastasis in a 10-week animal model of uveal melanoma. One million 92.1 human primary uveal melanoma cells were injected into the suprachoroidal space of the right eye of 27 immunosuppressed albino rabbits."

"Intraocular tumor growth was monitored weekly by fundoscopy and by ultrasonography at the end of the experiment. To document the progression of the disease, one animal per week was killed. The enucleated eyes, lungs, and livers were...

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