Cord Blood

Thawing and washing results in a substantial loss of umbilical cord blood cells

Published in Blood Weekly, February 2nd, 2006

Thawing and washing results in a substantial loss of umbilical cord blood cells.

According to a study from the United States, "Engraftment after umbilical cord blood (UCB) transplantation is highly dependent on nucleated cell (NC) and CD34+ cell content.

"Current standard post-thaw (PT) processing includes a wash step to remove dimethyl sulfoxide (DMSO), lysed red cells, and stroma. The contribution of the wash step to cell loss and ultimately the dose of cells available for transplant have yet to be systematically reported."

"This study examines the effect of the wash step as well as that of PT storage on various quality control...

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Source: Blood Weekly (2006-02-02)

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