Published in Blood Weekly, February 2nd, 2006
According to recent research from Germany, "In routine diagnostic procedures of AML, the FAB and WHO classifications both play a central role. Some morphologic subtypes are specifically associated to distinct cytogenetic and molecular aberrations; however, such close correlations do not exist for the majority of entities."
"We evaluated cytogenetics in 2,235 patients at diagnosis of AML with the FAB subtypes M0-2, M4, and M5-7. The cytogenetic patterns of these subtypes showed differences with respect to the clonal...
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