Blood Weekly
Susan Hasty, Publisher
Table of Contents . . . February 16th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Biomedical Engineering - Mild hypothermia preserves bioartificial liver loaded with freshly isolated liver cells
Blood Banking - Germ-free closed system developed for clinical banking of umbilical cord blood
Blood Transfusion - RhD typing for blood transfusion is not needed in southeast Asian populations
Cryopreservation - Trehalose improves cryopreservation of human embryonic stem cells
Tissue Engineering - Chondrocyte-seeded constructs better than unseeded carrier material for knee defect repair
Adult Stem Cells - Powerful technique for multiplying adult stem cells may aid therapies
Age-Related Macular Degeneration - Study shows protein that stimulates blood vessel growth also can block growth in AMD
Amputation - Sarcoma identified as leading cause of limb amputation
Autoimmune Disease Research - Research uncovers unlikely mediator linking autoimmune disorders and anemia
Bioethics - Human embryo cloning prohibited in Hong Kong
Blood Safety - A. xylosoxidans subsp. xylosoxidans cause of catheter-related bacteremia outbreak
Blood Safety - Catheter-associated K. oxytoca and E. cloacae outbreak occurred in chemotherapy center
Blood Safety - Study questions recent policy on screening of U.S. blood donations for WNV
Blood-Brain Barrier - Actin may play a critical role in modulating the blood-brain barrier
Bone Marrow - Blimp-1 is required for formation and maintenance of long-lived plasma cells
Brain Cancer - Anti-angiogenic therapy in pediatric neuro-oncology discussed
Breast Cancer - High-dose chemotherapy improved survival in breast cancer patients
Business Update - Cord blood banking business expanded into India
Business Update - Diagnostics company receives $1.2 million order for Chagas STAT-PAK rapid test
Cancer Immunology - Interleukin-1 receptor antagonist arrests the oncological effects of interleukin-1 beta
Cancer Inhibition - Polymeric polyphenols inhibited hematologic tumor cell lines
Cancer Prognostics - White blood cell count, inflammation predict cancer deaths
Cancer Therapy - Cancer phenotypes are suppressed through a multifunctional actin-binding protein
Cancer Therapy - Meisoindigo curtails angiogenic processes in chronic myelogenous leukemia cells
Candidiasis - Central venous catheters should be removed from patients with disseminated candidiasis
Cardiogenic Shock - In-hospital and in-transit extracorporeal membrane oxygenation have similar outcomes
Cardiology - Miniaturized CPB reduces safety margins but does not affect inflammation or blood loss
Cardiology - Recent studies add new data to cardiology research
Cardiovascular Disease - C-reactive protein contributes to hypercoagulable state in coronary artery disease
Cardiovascular Disease - Multi-organ dysfunction is intrinsic risk factor for tetralogy of Fallot repair
Cardiovascular Research - Scientist substantiate causal relationship between cocoa compounds and cardiovascular health
Chronic Renal Failure - Citrate anticoagulation may be safe for chronic renal failure patients on hemodialysis
Clinical Trials - Cholesterol drug's safety reconfirmed in analysis of 49 clinical trials, developer reports
Clinical Trials - Cocaine vaccine prevents cocaine from getting out of the blood stream
Clinical Trials - Stem cell-focused biotech company announces upcoming human trials for stroke therapy
Complementary & Alternative Medicine - Alternative medicine remedies might stimulate leukemic cell viability
Cord Blood - Private stem cell therapy company contributes 250th cord blood stem cell transplant
Coronary Artery Bypass - Studies add new findings to coronary artery bypass body of knowledge
DNA Research - PCR technique supports DNA sequencing for accurate diagnosis of candidemia
Diabetes Pathogenesis - High oxidative stress and endothelial dysfunction in PM exposed rats raised CVD risk
Diabetes Therapy - Biphasic insulin aspart 30 maintains postprandial BG better than traditional insulin
Diabetes Therapy - RSG lowers insulin needs and C-reactive protein levels in diabetics receiving dialysis
Diabetes Therapy - Services from clinical pharmacists improved A1C values, blood pressure, and aspirin use
Diagnostics - Mean arterial pressure superior to systolic BP for hypotension diagnosis
Diagnostics - Novel assay facilitates diagnosis of organic acid and fatty acid oxidation disorders
Diagnostics - Rapid enzyme-linked assay for ADAMTS-13 developed
Diagnostics - Scripps clinic acquires BVA-100 blood volume analyzer
Diet & Nutrition - Protein S and Gas6 stimulate retinal pigment epithelial outer segment phagocytosis
Diet & Nutrition - Review suggests diet is more effective than exercise in lowering blood pressure
Disease Associations - No relation found between Thr789Ala vWF gene variant and coronary heart disease in diabetics
Disease Control - Bartonella henselae isolated from porpoise blood
Drug Development - Multiple Myeloma Research Consortium selects preferred contract research organization
Drug Development - Phase II/III pediatric trial initiated with Defibrotide to prevent veno-occlusive disease
Drug Safety - Oral rapamycin reduces restenosis risk after stenting
Drug Safety - Orlistat and micronized fenofibrate are safe and effective for overweight and obese
Embryogenesis - Failed fertilized oocytes are not effective recipients for somatic cell nuclear transfer
Embryonal Cancer - Embryonic environment can 'normalize' tumor cells during postimplantation development
Fanconi Anemia - Frog eggs help researchers understand Fanconi anemia
Gene Therapy - Aldehyde dehydrogenase gene targeting produces high acetaldehyde levels
Gene Therapy - Proangiogenic gene therapy may improve thrombus recanalization
Genetics - Alpha-spectrin gene mutation detected in hereditary pyropoikilocytosis kindred
Genetics & Genomics - Alterations occur in early maturation of FMRP-deficient NSCs in fragile X syndrome
Genetics & Genomics - Linkage analysis to identify QTL can lead to insulin resistance gene identification
Graft-versus-Host Disease - CD8+ SCs identified that generate and sustain allogeneic T-cell subsets in GVHD reactions
HIV/AIDS Blood Safety - Cobas Ampliscreen HIV-1 test detected blood donor seroconversion from minipool
Helicobacter Pylori - H. pylori-positive gastric mucosa is associated with lymphoid lymphoma
Hemangioendothelioma - Wide local excision recommended for epithelioid hemangioendothelioma
Hematology - Angiogenic factors may influence the outcomes of adults with acute lymphoblastic leukemia
Hematology - High dose factor VIIa improves clot structure and stability
Hemodialysis - Autogenous brachial artery-brachial vein fistula suitable for vascular access
Hemodialysis - Optodilutional and ultrasound dilution AV access tests produce incomparable results
Hepatitis B Virus - Adefovir-resistant hepatitis B can be associated with viral rebound and hepatic decompensation
Hodgkin Disease - Creation of a breast health program for female survivors of Hodgkin disease advocated
Human T-Cell Lymphotropic Virus - Tenofovir protects peripheral blood mononuclear cells against HTLV-1 infection
Hypertension - Animal model used to explore connexin gene's role in high blood pressure
Hypertension - Conn syndrome patients have intraoperative increases in blood pressure
Hypertension - National blood pressure survey in Eritrea finds hypertension is related to BMI
Hypertension - The role of single sugars and fatty acids in hypertension are reviewed
Imaging - Ultrasound image-guided cardiac cell delivery safe and effective
Iron Deficiency - Dialysis products manufacturer completes phase III trial protocol for iron-delivery product
Kidney Transplantation - Cystatin C-based equations are more accurate at predicting GFR in renal transplant recipients
Leukemia - Allo-BMT reduced relapse risk of leukemia but did not improve survival
Leukemia - Changes in bone mineral density in survivors of childhood leukemia analyzed
Leukemia - Coping linked to survival in leukemia patients with bone marrow transplants
Leukemia - Dose intensification improves outcome of leukemia
Leukemia - Elderly patients with acute lymphoblastic leukemia treated with imatinib
Leukemia - Importance of cytogenetics in diagnosis of leukemias assessed
Leukemia - Leukemia xenografts are inhibited by adenovirus-mediated tissue inhibitor
Leukemia - Move towards pathogenesis-oriented therapy of acute myeloid leukemia warranted
Leukemia - New findings in leukemia described
Leukemia - New findings in the area of leukemia detailed
Leukemia - Outcome in childhood acute myeloid leukemia found to be still unsatisfactory
Leukemia - Poor treatment outcomes in children with leukemia owed to low remission rate
Leukemia - Recent findings in leukemia described
Leukemia - Research in leukemia provides new insights
Leukemia - Researchers publish new studies and findings in the area of leukemia
Leukemia - TRAIL proposed as anticancer agent in acute myeloid leukemia
Leukemia - Treatment concepts of acute promyelocytic leukemia discussed
Leukemia - Verapamil analogues display multidrug reverting activity toward leukemia cells
Liver Disease - Endotoxemia and its effects influence the progression of severe alcoholic liver injury
Lupus Nephritis - Ccr2 is a potential target for the treatment of lupus nephritis
Lymphangiogenesis - Bone marrow-derived circulating progenitor endothelial cells aid lymphatic vessel formation
Market Analysis - More angiogenesis inhibitors expected to reach market in next 5 years, according to report
Medical Devices - Antibody screening, blood typing systems ordered by blood donor testing firm
Medical Devices - Left driving pressure slope useful for estimating valve cavitation in electro-hydraulic heart
Medical Devices - Scripps Hospital acquires blood volume analyzer
Mergers & Acquisitions - Cord Blood America acquires assets of New York umbilical cord blood company
Mergers & Acquisitions - Dialysis provider purchases remaining shares of Renaissance and Optimal
Multiple Myeloma - FDG-PET detected more lesions than MIBI scan in patients with multiple myeloma
Myeloma - Lenalidomide plus dexamethasone is a highly active regimen for newly diagnosed myeloma
Myocardial Infarction - Therapeutic stem cell transplantation studied in heart attack patients
Neurodegeneration - G-CSF is a neurotrophic factor and may be used to treat neurodegenerative disorders
Neurogenesis - EGF and FGF-2 infusion increases postischemic neural progenitor cell proliferation
Neuropeptides - Blockade of angiotensin II AT1 receptors inhibits pressor action
Nuclear Medicine - Standards authority reports on safety of nuclear medicine procedures
Obesity Complications - Obese adults with hypertension have an increased risk for chronic kidney disease
Oral Surgery - Platelet releasate augments periodontal regenerative therapy in canine models
Pancreatic Cancer - Congenital anomalies of spleen mimicked hematological disorders and solid tumors
Patents - U.S. patent issued for photoselective vaporization methods of prostate and other tissues
Peripheral Arterial Disease - Inflammation markers tied to narrow, blocked arteries
Peritoneal Dialysis - Gender and body type affect optimal catheter selection and placement
Pharmacology - AUC from 0 to infinity estimated in serial sacrifice designs
Philanthropy - Financial services company extends commitment to underwrite children's health organization events
Philanthropy - Pharma company announces $750,000 donation for new translational transplant research laboratory
Physiology - Microtubules have differential roles in megakaryocyte proplatelet formation
Prostate Cancer - Complete androgen ablation suppresses PSCA mRNA expression in prostate cancer
Pulmonary Biology - Pneumocystis-stimulated lung damage depends on MHC class I expression
Pulmonary Embolism - Model may help identify pulmonary embolism patients with low mortality risk
Pulmonary Physiology - Endothelial targeting facilitates thrombolysis in pulmonary vasculature
Quality Assurance - First nonprofit research organ and tissue bank to receive AATB accreditation announced
Quality Assurance - U.K. Stem Cell Bank role reviewed in providing access to human stem cell seed stock lines
Sleep Apnea - Daytime sleepiness is linked to significant increase in ischemic cardiac events
Stem Cell Research - ATR/Chk1 pathway inhibition induces a p38-dependent S-phase delay in ESCs
Stem Cell Research - Adult cardiomyocytes can divide
Stem Cell Research - Astrocytes increase production of embryonic stem cell-derived neural stem cells
Stem Cell Research - Caveolin-1 deficiency induces mammary stem cell accumulation
Stem Cell Research - Cell-to-cell contact is required for hematopoietic progenitor cell survival
Stem Cell Research - Chemokines guide endothelial progenitors to new tumor vessels
Stem Cell Research - CordLife is southeast Asia's first accredited cord blood bank
Stem Cell Research - Embryonic stem cells have potential to produce renal primordial duct structures
Stem Cell Research - Endomucin marks hematopoietic stem cells throughout development
Stem Cell Research - Enhanced stem cell antigen-1 in lymphocytes correlates with lupus disease severity
Stem Cell Research - Epidermal growth factor stimulates embryonic stem cell proliferation
Stem Cell Research - Fibroblast cell lines have characteristics of ESC and cells of neuroectodermal origin
Stem Cell Research - Fibroblast growth factor-dependent Notch signaling maintains spinal cord stem zone
Stem Cell Research - Human omental stem cells generate new vessel growth
Stem Cell Research - Lentiviral expression of Pdx1- and Pdx1-VP16 reprograms liver-stem WB cells
Stem Cell Research - Nephrogenic factors promote ESC differentiation into renal epithelia
Stem Cell Research - Umbilical cord Wharton's jelly-derived MSCs differentiate into nerve-like cells
Stem Cell Research - rAAV transduction determines osteoprogenitor-specific promoter activity in mesenchymal stem cells
Stem Cell Transplantation - CD3/CD19-selected grafts advantageous for engraftment and immunoreconstitution
Stem Cell Transplantation - Hair follicle stem cells implants used to repair severed peripheral nerves
Stem Cell Transplantation - Procedure developed to highly purify NK cells for immunotherapy after haploidentical SCT
Stem Cell Transplantation - Recent studies add new data to stem cell transplantation research
Stroke - Aspirin therapy may be safe for some survivors of brain hemorrhage
Tissue Engineering - Method prepares coaxial electrospun nanofibers for controlled bioactive agent release
Tissue Engineering - New findings in the area of tissue engineering detailed
Toxicology - Shiga toxins promote endothelial-cell secretion and impair cleavage of von Willebrand factor multimers
Transplant Medicine - Adenoviral bcl-2 transfer improves post-transplantation survival and early graft function
Transplant Medicine - Artificial ureters remain unobstructed following renal transplantation
Transplant Medicine - Carbon monoxide protects transplanted kidneys in rats
Transplant Medicine - Non-invasive technique detects heart transplant rejection at cellular level
Transplant Medicine - Noninvasive technique developed to detect transplant rejection at cellular level
Transplant Medicine - Organ and tissue donation on the rise in Colorado and Wyoming, 395 lives saved in 2005
Transplant Medicine - Plasmapheresis may lower risk of recurrent focal segmental glomerulosclerosis
Transplant Medicine - Researchers report details of new studies and findings in the area of transplant medicine
Transplant Medicine - Study identifies risk factor for impaired renal function after kidney and pancreas transplant
Type 1 Diabetes - Intensive diabetes treatment improves cardiovascular disease risk in type 1 diabetics
Vancomycin - Limited blood sampling approach is required to determine blood concentrations of vancomycin
Vascular Medicine - Tiny ultrasound dissolves clots faster, more effectively
Von Willebrand Disease - von Willebrand factor mutations cause intracellular retention
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