Transplant Medicine
Adenoviral bcl-2 transfer improves post-transplantation survival and early graft function
Published in Blood Weekly, February 16th, 2006
"Primary graft dysfunction due to ischemia and reperfusion injury represents a major problem in liver transplantation. The related cell stress may induce apoptosis, which can be suppressed by bcl-2."
"The purpose of the study was to investigate the effect of adenoviral bcl-2 gene transfer on early graft function and survival in rat liver transplantation," wrote M. Rentsch and colleagues, University of Regensburg.
"An adenoviral construct that transfers bcl-2 under the...
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Source: Blood Weekly (2006-02-16)
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