Transplant Medicine

Carbon monoxide protects transplanted kidneys in rats

Published in Blood Weekly, February 16th, 2006

Carbon monoxide, a highly toxic gas often called the "silent killer," may prove useful for extending the life of transplanted organs, suggests a University of Pittsburgh study.

Researchers found prolonged, low-dose exposure to be protective against chronic rejection in a rat kidney transplant model. Chronic rejection is the primary reason that patients require second or third transplant operations.

In the study, to be published in an upcoming issue of the American Journal of Physiology-Renal Physiology and available online, senior author Noriko Murase, MD, associate professor of surgery at the Thomas E. Starzl Transplantation Institute,...

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Source: Blood Weekly (2006-02-16)

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