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Leukemia

Allo-BMT reduced relapse risk of leukemia but did not improve survival

Published in Blood Weekly, February 16th, 2006

Allogeneic bone marrow transplant (allo-BMT) could reduce the relapse risk of acute myeloid leukemia (AML) but does not improve survival.

"Between 1988 and 2002, 758 children with AML were treated on Medical Research Council (MRC) AML 10 and AML 12. MRC AML 10 tested the role of bone marrow transplantation following four blocks of intensive chemotherapy and found that while both allo-BMT and autologous bone marrow transplant (A-BMT) significantly reduced the relapse risk (RR), this did not translate into a significant improvement in overall survival (OS)," scientists writing in the journal Leukemia reported.

"A risk group stratification based...

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