Published in Blood Weekly, February 16th, 2006
According to a study from Germany, "Genetic and molecular techniques have provided increasing insights into the biology of AML. These investigations showed that AML is not a homogeneous disease but a heterogeneous group of biologically different subentities."
"These subentities are currently primarily defined by cytogenetics by which 3 main subgroups can be discriminated: AML with balanced translocations, AML with unbalanced aberrations and AML without cytogenetically detectable aberrations. Within the latter group molecular alterations are identified in...
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