Stem Cell Transplantation
Mobilized CD34+ stem cells expanded for clinical use in serum-free medium
Published in Blood Weekly, February 23rd, 2006
According to a study from France, "The autologous transplantation of CD34+ cells expanded ex vivo in serum-free conditions dramatically reduces postmyeloablative neutropenia in myeloma patients.
"In our cell therapy unit, cells for this clinical assay have been expanded under GMP with serum-free Irvine Scientific (IS) medium with stem cell factor (SCF), granulocyte-colony-stimulating factor (G-CSF), and megakaryocyte growth and development factor (MGDF; 100 ng/mL, respectively)."
"Because this clinical-grade IS medium is no longer...
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Source: Blood Weekly (2006-02-23)
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