Published in Blood Weekly, March 2nd, 2006
"In the present study, we investigated the effect of aging on spermatogonial stem cells (SSCs) and on the testicular somatic environment in ROSA26 mice. First, we examined testis weights at 2 months, 6 months, 1 year, and 2 years of age.
"At 1 and 2 year, bilateral atrophied testes were observed in 50 and 75% of the mice, respectively; the rest of the mice had testis weights similar to those of young mice," scientists in Canada report.
According to the authors, "Next, we evaluated the number and the activity of aged SSCs using...
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