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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . March 9th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Blood Banking - Optimized method filters buffy coats as a replacement for standard buffy coats

Blood Banking - Sample errors account for majority of near-miss events in blood transfusions

Cardiac Allograft - Lymphoid sequestration of alloreactive CD4 cells promotes cardiac allograft survival

Stem Cell Transplantation - HLA-DPB1 matching status in HSCT associated with increased risk of disease relapse

Stem Cell Transplantation - p18(INK4C) deletion results in improved long-term HSC engraftment

Alcoholic Hepatitis - ADAMTS13 may contribute to multiorgan failure in alcoholic hepatitis

Alcoholic Hepatitis - Severe alcoholic hepatitis ascertained in Japan

Angiology - Report on U.S. angiography labs shows higher budgets for capital equipment, less for film

Antioxidant Research - Mitochondrial targeted antioxidants may offer a new therapeutic direction

Arthroplasty - Wound compression reduces blood loss after total hip replacement

Benign Prostatic Hyperplasia - Preoperative dutasteride may reduce intraoperative bleeding during transurethral prostate surgery

Bioreactor - Model accurately predicts dissolved oxygen consumption within a hepatic fiber bioreactor

Bone Marrow Transplantation - Allogeneic BMT and patient eligibility based on psychosocial criteria

Bone Marrow Transplantation - Use of alternative donor transplants in children with early Ph+ ALL encouraged

Burkitt Lymphoma - Expression of BIC and miR-155 is not a common finding in Burkitt lymphoma

Business & Finance - Advate achieves one billion unit milestone

Cancer Diagnostics - Positron emission tomography used to detect bone marrow involvement in lymphoma

Cancer Incidence - Incidence of cancer around Amsterdam Airport Schiphol analyzed

Cancer Research - Perchloroethylene exposure affects various pathways involved in cancer induction

Cancer Therapy - Sirolimus reduces risk of cancer in kidney transplant patients, published study shows

Cancer Vaccine - Commercial launch of telomerase-immortalized cell line through ATCC announced

Cardiology - Data advance knowledge in cardiology research

Chronic Myeloid Leukemia - Test launched to monitor Gleevec resistance

Cloning - Mouse cloning improved by trichostatin a treatment after somatic nuclear transfer

Cloning - Nuclear transfer embryonic stem cells improve cloning from somatic cells

Collaborations - Deal signed with University of Nebraska-Lincoln for drug delivery system

Colorectal Cancer - Mutations spread in the normal colon by crypt fission

Cytomegalovirus - Fast track status granted to maribavir for prevention of cytomegalovirus infection

DNA Research - Fragmented nucleosomal DNA unrelated to caspase-3 mRNA in lymphoma and myeloma

Diagnostics - Three-year Novation agreement for microbiology blood culture instruments and media signed

Diet & Nutrition - Red grapefruit appears to lower cholesterol, fight heart disease

Disease Associations - Incidence of detecting pulmonary embolisms with CT in oncology patients analyzed

Disease Associations - Insulin resistance is associated with steatosis in chronic hepatitis C

Drug Development - Dasatinib may affect neoplasms associated with gain-of-function KIT mutations

Drug Development - The cyclolignan picropodophyllin may treat multiple myeloma

Drug Safety - Aprotinin reduces blood loss and thrombosis risk in off-pump heart bypass surgery

Drug Safety - Imatinib mesylate effective in CML in late chronic and advanced phase and after SCT relapse

Finance - Cardiology devices maker reports new $20 million stock repurchase program

Finance - Maker of blood processing systems reports Q2 2006 revenues of $3,127,000, up 6% from year ago

Genetics & Genomics - Gene expression patterns correlate with early progression to fibrosis in liver transplants

Hematology - A vascular wall protein inhibits collagen-induced platelet aggregation

Hematology - Thrombin autoantibodies target both of its cryptic exosites

Hemodialysis - Reports describe recent advances in hemodialysis research

Hepatitis C Virus - Early preservation injury may predict poor outcome after liver transplantation

Hypertension - Recent studies add new data to hypertension research

Kaposi Sarcoma Risk Factors - Kaposi sarcoma risk higher in HIV/AIDS than in transplant recipients

Keratoconjunctivitis - Treating childhood phlyctenular keratoconjunctivitis with topical cyclosporine A reported effective

Leukemia - Chromosomal translocations associated with poor prognosis in leukemia

Leukemia - Combined treatment with BB-1 and TRAIL proposed as new cancer therapy strategy

Leukemia - Decitabine induces apoptosis in acute myeloid leukemia

Leukemia - Findings describe new data in leukemia research

Leukemia - HFE gene mutations are not risk factors for leukemia in Mexican mestizos

Leukemia - Reports advance knowledge in leukemia research

Leukemia - Researchers' findings advance leukemia research

Leukemia - Researchers' work adds to leukemia body of knowledge

Leukemia - Studies add new findings to leukemia body of knowledge

Leukemia - Studies describe new findings in leukemia research

Lymphoma - Aberrant HGF-activator expression implicated in diffuse large B-cell lymphoma

Lymphoma - Phosphatidylinositol-3 kinase/Akt inhibition promoted apoptosis in Hodgkin lymphoma

Medical Devices - New service enables anticoagulant patients to self-test levels at home

Medical Devices - Pumpless extracorporeal lung assist device may aid treatment of severe ARDS

Medical Devices - Spot-check device introduced

Medical Devices - UHMW-PE wear particles influence bone marrow cell differentiation in vitro

Medical Devices - Vanderbilt University Medical Center acquires second BVA-100 blood volume analyzer

Mergers & Acquisitions - Disease management company closes sale of rapid cardiac immunoassay test business

Myeloid Tumors - Sox4 cooperates with Evi1 in AKXD-23 myeloid tumors

Nerve Injury - Peripheral nerve injury may be treated with exogenous tissue plasminogen activator

Neurogenesis - Transforming growth factor beta increases neurogenesis in adult dentate gyrus

Obesity Therapy - Findings describe new data in obesity therapy research

Oncology - Bortezomib uses alternate signals to control multiple myeloma angiogenesis

Oncology - Researchers detail new studies and findings in the area of oncology

Patents - Biotech company files patent application for expanding hematopoietic stem cells

Proteomics - Ets1-related protein initiates vasculogenesis in zebrafish

Sepsis - Useful treatments identified for severe sepsis and septic shock

Sickle Cell Anemia - Sickle cell anemia treated by coregulating globin transgene expression and RNA interference

Sickle Cell Disease - Protein reduces inflammation, inhibits vaso-occlusion in mice with sickle cell disease

Stem Cell Research - CTL response is not elicited by allogeneic MUC class I molecules

Stem Cell Research - Cord blood-derived MSCs can be chemically transformed into cardiomyocytes

Stem Cell Research - Exogenous VEGF has biphasic effects on adult neural progenitors

Stem Cell Research - Fibroblast growth factor receptor 1 not essential for lens fiber differentiation

Stem Cell Research - LIGHT induces ESC differentiation associated with activation of ERK5

Stem Cell Research - Multipotent stem/progenitor cells present in neonatal and adult salivary glands

Stem Cell Research - Primary bone-derived cells induce osteogenic differentiation

Stem Cell Therapy - Bone marrow stromal cells may be used to treat neurodegenerative and neurotraumatic diseases

Stem Cell Transplantation - Donor KIR genotype has major influence on CMV reactivation rate after T-cell replete SCT

Stem Cell Transplantation - IFNG 3/3 gene polymorphism associated with increased risk for EBV reactivation after AHSCT

Stem Cell Transplantation - Researchers publish new studies and findings in the area of stem cell transplantation

Stem Cell Transplantation - SCT with reduced-intensity conditioning favorable for hemophagocytic lymphohistiocytosis

Stem Cell Transplantation - Younger children more susceptible to growth retardation after total body irradiation and SCT

Thrombosis - Eosinophil peroxidase product induces endothelial cell tissue factor activity

Tissue Engineering - Researchers' data advance tissue engineering research

Transplant Medicine - California organ procurement organization posts 10% increase in organs transplanted in 2005

Transplant Medicine - Cyclosporine suppresses hepatitis C virus after liver transplantation

Transplant Medicine - Heart transplant followed by SCT feasible in select cardiac AL amyloidosis patients

Transplant Medicine - New findings in the area of transplant medicine detailed

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