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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . March 23rd, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Arthroplasty - Knee replacement postoperative unwashed shed blood use does not alter immunosuppression

Blood Safety - Risk of variant CJD transmission from blood products decreased in U.K.

Blood Safety - Sulfadoxine-pyrimethamine added to donor blood eradicates transfusion-induced malaria

Cord Blood - Cord blood stem cells clonogenic capacity not impaired by cryopreservation

Tissue Engineering - Functional corneal endothelial cell sheets fabricated for ocular surgery and repair

Adverse Drug Reaction - Public health advisory for Trasylol issued by U.S. FDA

Allergy & Immunology - ImmunoCAP Phadiatop Infant allergy test detects IgE sensitization in 2-year-olds

Anemia - Health Canada authorizes ProMetic BioSciences to begin Ib/II trial of PBI-1402 for anemia

Angiology - Anti-SDF-1 treatment prevents retinal neovascularization in nonhuman primates, study shows

Angiology - Coronary artery stenting is feasible even with intraluminal thrombus

Angiology - Research in angiology provides new insights

Apoptosis - Antimonial compounds may work by disrupting thiol homeostasis

Apoptosis - Retinoblastoma plays a role in survival of Abl-dependent human tumor cells

Blood Safety - Blood-borne infectivity study shows dramatic reduction in TSE prions

Bone Marrow - Bone marrow failure compared in male vs. female rats

Bone Marrow - Bone marrow suppression induced by bacterial infection prolonged after influenza infection

Bone Marrow Transplantation - Fetal tolerance to maternal antigens improves BMT outcome by CD4+CD25+-dependent mechanism

Business Update - Blood safety scientific advisory board established by Cerus

Cancer Therapy - Antifungal treatment for patients on chemotherapy deemed cost-effective

Cancer Therapy - High-dose cyclophosphamide may be unnecessary therapy for lymphoid malignancies

Cancer Therapy - New findings in cancer therapy described

Cancer Therapy - Phenylcarbazoles display antitumor properties

Cancer Therapy - Researchers' data advance cancer therapy research

Candida - U.S. FDA approves new treatment for fungal infections

Cardiology - Angiogenesis and cardiac function improve following bone marrow cell implantation

Cardiology - Studies describe new findings in cardiology research

Cardiovascular Research - Artificial matrix helps neonatal cardiomyocytes restore injured myocardium

Carotid Body Tumor - Current concepts for surgical management of carotid body tumor discussed

Cell Biology - Adult angiogenesis is enhanced by accessory cells

Clinical Trials - Clinical study of small molecule Telintra tablet for myelodysplastic syndrome initiated

Clinical Trials - Synthetic Blood expects to start trial in Q2 2006 on oxygen carrier in sickle cell anemia

Colon Cancer - Tissue block types should be scanned for venous invasion in colorectal carcinoma

Contraception - Ortho Evra study shows risk of VTE and DVT similar to oral contraceptives

Contracts - RTS Life Science secures contract for automated blood fractionation system

Dengue Fever - Dengue antigen developed

Diabetes Therapy - Data advance knowledge in diabetes therapy research

Diagnostics - Atorvastatin HPLC assay developed

Diagnostics - CE IVD-marked products launched in Europe by Cepheid

Diagnostics - Cell membrane microparticles are possible pathogenic agents and diagnostic markers

Disease Associations - Incidence of venous thromboembolism studied in patients hospitalized with cancer

Drug Development - Arixtra shown to reduce risk of venous thromboembolism in acutely ill patients

Drug Development - Compound with smaller diluent for treating von Willebrand disease now available

Ebola Vaccine - Ebola vaccine with Vical technology produces immune responses in trial volunteers

Encephalitis - Heparan sulfate mimetic PI-88 demonstrated a beneficial effect on encephalitic flaviviruses

Facilities - Novo Nordisk opens hemostasis research facility in New Jersey

Finance - Endovascular device company reports Q4 2005 net sales up 60% to $41 million over year ago

Finance - Gen-Probe reports Q4 net income of $16.8 million

Finance - Medwave raises over $4.43 million in capital

Graft-vs-Host Disease - Positive new survival findings from phase II, III orBec trials presented by DOR BioPharma

Hematology - Platelets promote angiogenesis but thwart hemorrhage

Hematology - Researchers' work adds to hematology body of knowledge

Hepatitis A Virus - HAV detection in clotting factors implicated as a source of infection

Hepatitis C Virus - Volunteer blood donors with hepatitis C experience a worse quality of life

Hodgkin Lymphoma - ALK-positive anaplastic large cell lymphoma mimicked nodular sclerosis Hodgkin lymphoma

Hypertension - Studies advance knowledge in hypertension research

Inflammatory Bowel Disease - Exclusive worldwide rights to Simulect for inflammatory bowel disease licensed to Cerimon

Kidney Transplantation - HHV8 prevalence is low in renal donors and recipients in Greece

Kidney Transplantation - Postrenal transplantation weight gain assessed

Leukemia - Adult acute megakaryocytic leukemia confirmed to have poor prognosis

Leukemia - Apoptosis of leukemia cells induced by mycotoxin citrinin

Leukemia - Bayesian methods used in detection of changes in childhood cancer incidence

Leukemia - Chronic lymphocytic leukemia linked to CpG island methylation

Leukemia - Human T-cell leukemia virus oncoprotein inhibits Fas-mediated apoptosis

Leukemia - Scoring system to distinguish elderly leukemia patients with different prognosis proposed

Leukemia - Tyr phosphorylation modulates binding preference in leukemia cells

Leukemia Therapy - Clinical benefit analysis of Genasense plus chemotherapy reported

Limb Allograft - Limb allograft survival prolonged by donor leukocytes and delayed immunosuppressive therapy

Lung Transplantation - Morbidity and mortality high in lung transplant patients with untreated pulmonary TB

Mast Cells - Tryptase- and chymase-related gene clusters identified in human mast cells

Medical Devices - Artificial liver support system safe and effective in acute or chronic liver failure

Medical Devices - Smiths Medical MD to distribute medComp's Split Stream catheters for hemodialysis

Multiple Myeloma - Multiple myeloma treated with bendamustine and prednisone

Nephrology - Tailoring fluid replacement and anticoagulation therapy increases metabolic control

Neurogenesis - ATBF1 induces cell cycle arrest associated with neuronal differentiation

Neurogenesis - Neural stem cells in adult ciliary epithelium express GFAP and are regulated by Wnt signaling

Neuroscience - Erythropoietin enhances neuroprotection against ischemia and reperfusion injury

Nosocomial Infections - Pfizer receives U.S. FDA approval for Eraxis to treat candidemia

Oncology - Complications in cancer patients with central venous catheters were not prevented with dalteparin

Oncology - Researchers publish new studies and findings in the area of oncology

Organ Donation - Record number of organs recovered for transplantation reported by Gift of Life Michigan

Patents - Alexion issued key patent for eculizumab in Japan

Pediatric Cardiology - Child with Omenn syndrome was also diagnosed with ventricular thrombosis

Pharmaceutical Research - Recombinant antithrombin inhibits thrombin formation and interleukin release in endotoxemia

Philanthropy - Ten million dollars contributed to M. D. Anderson research effort by Gita, Ali Saberioon

Polycystic Ovary Syndrome - Reports add new data to polycystic ovary syndrome research

Product Licensing - Yale technology for new early stage ovarian cancer blood test licensed to developer

Proteomics - Proteins governing angiogenesis and bone growth interact during osteoclastogenesis

Proteomics - Recent findings in proteomics provide new insights

SARS - Findings advance knowledge in SARS research

Spinal Cord Injury - Umbilical cord blood transplantation improves mobility after spinal cord injury

Stem Cell Research - Absence of Chx10 homeobox gene causes neural progenitors to persist in adult retina

Stem Cell Research - Embryonic stem cells assume a primitive neural stem cell fate in absence of extrinsic influences

Stem Cell Research - Human embryonic stem cell lines derived from embryos with monogenic disorders

Stem Cell Research - Mesenchymal stem cells modulate B-cell functions

Stem Cell Research - Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells

Stem Cell Research - Stem cells and their derivatives bypass myocardin requirement for smooth muscle gene expression

Stem Cell Transplantation - MRI detects transplanted ESCs and their therapeutic effect on injured myocardium

Stroke - Data show enzyme biomarker helps predict recurrent stroke risks in multi-ethnic population

Stroke - FG-4539 is neuroprotective and significantly reduces brain tissue damage, says FibroGen

Surgery Technology - Hemodialysis vascular access via autogenous brachial artery-brachial vein fistula effective

Tissue Bank - SRI Surgical signs agreement to distribute implant tracking system to tissue banks

Tissue Engineering - Reports describe recent advances in tissue engineering research

Transfusion Medicine - In pediatric cardiac surgery, hydroxyethyl starch is a safe alternative for volume replacement

Transplant Medicine - In kidney transplant recipients, ApoB polymorphism may adversely affect long-term survival

Transplantation Biology - Hepatitis C virus antigen detected in cholestatic hepatitis after liver transplantation

Transplantation Biology - Receptor polymorphisms are associated with long-term renal allograft survival

Wegener Granulomatosis - Wegener granulomatosis often diagnosed if destruction of the maxillary sinus' medial wall is found

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