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Tissue Engineering

Functional corneal endothelial cell sheets fabricated for ocular surgery and repair

Published in Blood Weekly, March 23rd, 2006

Functional corneal endothelial cell sheets have been fabricated for ocular surgery and repair.

"This study reports a new method for fabricating bioengineered human corneal endothelial cell sheets suitable for ocular surgery and repair. We have initially cultured human corneal endothelial cells on type IV collagen-coated dishes and, after several passages, expanded cells were then seeded onto novel temperature-responsive culture dishes," investigators in Japan report.

According to T. Sumide and colleagues at Osaka University, "Four weeks after reaching confluence, these cultured endothelial cells were harvested as intact monolayer cell sheets by...

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