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Alexion issued key patent for eculizumab in Japan

Published in Blood Weekly, March 23rd, 2006

Alexion Pharmaceuticals, Inc., (ALXN) reported that the Japanese Patent Office has issued Patent No. 3734266, entitled "Methods and Compositions for the Treatment of Glomerulonephritis and Other Inflammatory Diseases," which relates to the company's lead product, Soliris brand of eculizumab.

The issued claims encompass the use of Alexion's lead drug candidate, eculizumab, to inhibit complement activation in humans. Complement inhibition is the key mechanism of action for eculizumab in paroxysmal nocturnal hemoglobinuria (PNH), which Alexion is currently developing under the brand name Soliris.

"The issuance of this Japanese patent represents a key...

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