Tissue Regeneration
COX-2 inhibition attenuates BMP-6 synthesis and bone formation in tissue regeneration
Published in Blood Weekly, March 30th, 2006
According to a study from the United States, "Bone formation during guided tissue regeneration is a tightly regulated process involving cells, extracellular matrix and growth factors.
"The aims of this study were (1) to examine the expression of cyclooxygenase-2 (COX-2) during bone regeneration and (2) the effects of selective COX-2 inhibition on osseous regeneration and growth factor expression in the rodent femur model."
"A standardized transcortical defect of 5x1.5 mm was prepared in the femur of...
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Source: Blood Weekly (2006-03-30)
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