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Non-Hodgkin Lymphoma

Detection of bone marrow lesions improved by ferumoxtran-10-enhanced MR imaging

Published in Blood Weekly, April 6th, 2006

Detection of bone marrow lesions was improved by ferumoxtran-10-enhanced MR imaging.

According to a recent report, researchers in Germany conducted a study "to quantify permeability changes of the 'blood-bone marrow barrier' (BMB) and to detect malignant bone marrow infiltrations before and after conditioning therapy for subsequent leukapheresis using ferumoxtran-10-enhanced magnetic resonance (MR) imaging. Twenty-two patients with malignant non-Hodgkin lymphomas (NHL), including 9 patients (group A) before and 13 patients (group B) after conditioning therapy, underwent MR of the spine before and after infusion of ferumoxtran-10 (.045 mmol Fe/kg BW)."

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