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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . April 20th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Hematology - von Willebrand factor-mediated platelet thrombi size is regulated by ADAMTS13

Tissue Engineering - Collagen-glycosaminoglycan matrix developed for heart valve tissue engineering

Transplant Medicine - Unrelated cord blood transplant is an alternative for adults lacking HLA-matched donor

Acute Myeloid Leukemia - Acute myeloid leukemia patients with KIT-D816 mutations linked to poor prognosis

Acute Myeloid Leukemia - Acute myeloid leukemia treated by Filgrastim as an adjunct to chemotherapy

Acute Myeloid Leukemia - Autotransplantation increases 3-year survival for AML patients in first or second remission

Acute Myeloid Leukemia - Poor prognosis in pediatric acute myeloid leukemia linked to KIT mutations

Angiology - COX-1 and glycoprotein receptor polymorphisms are linked to antiplatelet effect of aspirin

Angiology - Homocysteine-induced endothelial dysfunction is augmented by iron sucrose in normal subjects

Awards - Sanaria Inc. CEO Stephen L. Hoffman named world's most cited author for malaria papers

Bone Marrow Transplantation-Associated Infection - Infections documented among children undergoing allogeneic BMT in India

Business Update - eFoodSafety.com announces first orders for blood sugar-regulating nutritional supplement

Cancer & Anemia - Risk factors for anemia in cancer patients receiving chemotherapy identified

Cancer Survival - Cancer survival among adolescents in France analyzed

Cancer Therapy - Cancer growth may be discouraged by CXCR4 antagonists

Cardiology - In acute coronary syndrome, aspirin plus warfarin was superior for adverse event prevention

Cardiovascular Disease - Cardiovascular mortality can be predicted by resistive index of internal carotid artery

Cardiovascular Disease - Oxidized low-density lipoproteins might be markers of destabilization of coronary artery disease

Cardiovascular Research - Grape seed extract may be effective in reducing blood pressure

Cardiovascular Research - Loneliness linked to high blood pressure in aging adults

Chronic Hepatitis C - Platelet activation in chronic hepatitis C is decreased by antiviral therapy

Chronic Liver Disease - Liver regeneration improves following endothelial progenitor cell transplantation

Clinical Trials - Results of trial support early treatment in non-ST-segment elevation ACS

Collaborations - Abaxis licenses lyophilization technology to bioMerieux

Collaborations - Lilly and Biosite sign agreement to collaborate on clinical trial of severe sepsis drug

Congenital Hemangiopericytoma - Congenital hemangiopericytoma in a neonate described

Contracts - Medwave's Primo blood pressure monitor added to existing Amerinet purchasing agreement

Cytomegalovirus - Asymptomatic congenital cytomegalovirus infection may be higher than currently estimated

Deep Vein Thrombosis - Hospital compliance with clot-prevention best practices needs improvement, says Premier

Developmental Biology - B-lineage precursors in bone marrow stimulated by a hybrid cytokine

Developmental Biology - Dentin phosphophoryn signaling involves activation of the smad pathway

Developmental Biology - Mesenchymal epimorphin is important for pancreatic duct morphogenesis

Diabetes Complications - Median duration to end-stage renal disease has been prolonged in patients with type 1 diabetes

Diabetes Pathogenesis - High platelet FcR expression and low LDL cholesterol levels more common in type 2 diabetes

Diabetes Therapy - Researchers' work adds to diabetes therapy body of knowledge

Diabetes Therapy - Studies describe new findings in diabetes therapy research

Diagnostics - Angiogenesis, inflammation, and growth deregulation cytokines convey patient factors

Diagnostics - Invasive aspergillosis excluded by nested PCR screening assay

Drug Development - Angiogenesis may be manipulated through asymmetric dimethylarginine regulation

Drug Development - Homogeneous embryonic stem-derived cell types isolated from heterogeneous populations

Drug Safety - Danish Medicines Agency withdraws Xanta, drug to treat blood clots after knee, hip surgery

Environmental Health - Blood coagulation impairments are likely after pulmonary zinc exposure

Gastroenterology - Intestinal alkaline sphingomyelinase inactivates platelet-activating factor

Genetics & Genomics - New findings in genetics & genomics described

HIV/AIDS Vaccine Development - HIV serodetection assay differentiates vaccine- from virus-induced antibodies

Hematology - In hypertension, normalized platelet activation may be a benefit of doxazosin GI therapeutic system

Hematology - In pediatric cardiac surgery, blood transfusions may be reduced with use of aprotinin

Hematology - Researchers publish new studies and findings in the area of hematology

Imaging - Transesophageal echocardiography can be essential to clarify stroke etiology

Imaging - Transesophageal echocardiography impacts management of patients with potential embolism

Kidney Disease - In uremic patients, calcification quantification shows association with cardiovascular dysfunction

Kidney Disease - Reports advance knowledge in kidney disease research

Leishmaniasis Therapy - Amphotericin B lipid formulations may be useful in leishmaniasis patients

Leukemia - Chronic lymphocytic leukemia cell survival is promoted by high Mda-7 expression

Leukemia - Death of Jurkat human leukemia cells induced by novel synthetic ceramide analogs

Leukemia - Findings describe new data in leukemia research

Leukemia - Leukemia inhibition of retinoic acid receptor signaling by Ski evaluated in acute myeloid leukemia

Leukemia - Leukemia treated by 131I-anti-CD45 antibody plus busulfan and cyclophosphamide

Leukemia - Leukemia-associated gain-of-function mutation affects interleukin-3 signaling

Leukemia - New findings in leukemia described

Leukemia - Protein kinase C-d announced as promising new target in chronic lymphocytic leukemia treatment

Leukemia - Recent findings in leukemia provide new insights

Leukemia - Researchers' data advance leukemia research

Leukemia - Response of leukemia to chemotherapy improved by administering cyclosporin-A

Leukemia - Wilms tumor 1 gene expression in human leukemic K562 cells inhibited by curcumin

Liver Transplantation - Liver transplantation use of tissue plasminogen activator is complicated by thrombosis

Marketing - Celebrity entrepreneur Farrah Gray signs on as spokesman for National Marrow Donor Program

Medical Devices - For Patients, Inc.'s CathSling has been approved for Medicare reimbursement

Medical Devices - St. Jude Medical launches vascular closure device for diagnostic, interventional procedures

Mergers & Acquisitions - Magistral Biotech sells its cholesterol-related assets to Diversified Natural Products, Inc.

Multiple Myeloma - Changes in multiple myeloma epidemiology in last 30 years reviewed

Myocardial Infarction - Cardiac tamponade occurs in <1% of patients with fibrinolytic-treated acute MI

Myocardial Ischemia - Stem cells mobilize after myocardial infarction when cell factor is added to treatment regimen

Neurogenesis - Neurotransmitters determine survival and differentiation of newly generated neurons

Neuroscience - Human neural progenitors deliver glial cell line-derived neurotrophic factor

Nucleic Acid Preservation - Lyophilized viral DNA and RNA stable even after prolonged storage

Obesity Pathogenesis - Research in obesity pathogenesis provides new insights

Obesity Pathogenesis - Researchers report details of new studies and findings in the area of obesity pathogenesis

Oncology - Studies describe new findings in oncology research

Pancreatic Cancer - Pancreatic cancer related to high risk of venous thrombosis after surgery

Penile Cancer - Penile metastasis from other malignancies reviewed

Personnel - Insulet Corp. names Ruthann DePietro vice president of quality and regulatory affairs

Platelet Aggregation - Immunoglobulin G plays a role in Streptococcus sanguis-induced platelet aggregation

Product Licensing - Genetic testing company Tm Bioscience acquires sepsis biomarkers from Sirius Genomics

Product Licensing - Orthovita enters license agreement with Angiotech for Vitagel surgical hemostat

Progenitor Cells - AKT induces erythroid-cell maturation of fetal liver progenitor cells

Proteomics - Findings describe new data in proteomics research

Psoriasis - Isotechnika announces preliminary data from phase III ISA247 psoriasis trial

Respiratory Medicine - Patients with chronic obstructive pulmonary disease harbor excess endothelial progenitors

Respiratory Syncytial Virus - Respiratory syncytial virus infects monocyte-derived dendritic cells

Rheumatoid Arthritis - In rheumatoid arthritis patients, preclinical atherosclerosis is prevalent

Solid Tumors - Outcome of solid tumors treated by bortezomib in combination with docetaxel assessed

Spermatogenesis - Spermatogonial stem cells undergo anchorage-independent self-renewal division in culture

Statins - Research add new data to statins body of knowledge

Stem Cell Research - Adult central nervous system stem cells express aquaporin channels

Stem Cell Research - Adult neural stem cell self-renewal suppressed by p53

Stem Cell Research - Aldagen's product used to isolate stem cells from cord blood

Stem Cell Research - Cerebellar neuron precursors generated from embryonic stem cells

Stem Cell Research - Clonal amniotic fluid-derived stem cells express MSC and NSC characteristics

Stem Cell Research - Expanded mesenchymal stem cells exhibit neuroepithelial or neural precursor cell markers

Stem Cell Research - Gata2 plus Sca1 expression defines hematopoietic stem cells in bone marrow niche

Stem Cell Research - Genomic data can be used to improve outcome of allogeneic hematopoietic cell transplants

Stem Cell Research - Hematopoietic stem cells modeled for autologous transplantation

Stem Cell Research - Jagged1 enhances differentiation of mesenchymal stem cells into cardiomyocytes

Stem Cell Research - La protein required for development and establishment of embryonic stem cells

Stem Cell Research - Muscle tissue formation from skeletal muscle stem cells is age dependent

Stem Cell Research - Notch, epidermal growth factor receptor and beta 1-integrin pathways coordinated in NSCs

Stem Cell Research - Progenitor cell differentiation is stimulated by thrombin and protease-activated receptor-1

Stem Cell Research - Skeletal muscle-derived progenitor cells exhibit neural competence

Stem Cell Research - Somatic cells reprogrammed by embryonic stem cell cytoplast

Stem Cell Research - Umbilical cord matrix cells have properties of primitive pluripotent stem cells

Stem Cell Transplantation - C-reactive protein release patterns after ASCT correlate with leukemic relapse

Stem Cell Transplantation - CMV reactivation after SCT associated with stronger humoral dominated immune response

Stem Cell Transplantation - Growth-chart-based evaluation stratifies children with inadequate growth after SCT

Stem Cell Transplantation - IL-7R alpha polymorphisms related to treatment-related mortality after SCT

Stem Cell Transplantation - Long-term donor health associated with recipient stem cell transplantation outcome

Stem Cell Transplantation - Researchers' work adds to stem cell transplantation body of knowledge

Tissue Engineering - Bilayered scaffold suitable for skin equivalent tissue engineering

Tissue Engineering - Biocompatible dural substitute replaces biological tissue without causing incompatibility

Tissue Engineering - Bone tumors were treated with tissue-engineered osteogenic ceramic implants

Tissue Engineering - Keratinocytes cultured without external supplements in conditioned media and feeder gel

Tissue Engineering - Researchers report details of new studies and findings in the area of tissue engineering

Tissue Sterilization - Clearant announces pre-mixed radioprotectant solution for CLEARANT PROCESS tissue sterilization

Total Body Irradiation - Hematopoietic stem cell senescence selectively induced by total body irradiation

Transplant Medicine - Positive results reported in animal diabetes experiments of pancreatic xenotransplantation

Transplant Medicine - Tissue transplantation case could create donation backlash

Women’s Health - Women's health findings presented at national gynecologic conference

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