Blood Weekly
Susan Hasty, Publisher
Table of Contents . . . April 27th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Cardiology - In high-transfusion-risk cardiac surgery, aprotinin and tranexamic acid are similarly effective
Hepatitis C Virus - Hepatitis C virus recurrence and graft fibrosis is treatable following liver transplantation
Tissue Engineering - Cell-cell competition replaces functional organ tissue under nonselective conditions
Tissue Engineering - Neural progenitor and endothelial cells cocultured on hydrogel forms functional vascular networks
Twin-to-Twin Transfusion Syndrome - U.S. FDA approves humanitarian device exemption for treatment of Twin-to-Twin Transfusion syndrome
Arterial Thrombosis - Targeting PAR1-PAR4 may offer opportunity to prevent arterial thrombosis
Bone Marrow - Bone marrow stromal cell proliferation and osteogenic potential is enhanced by osterix
Bone Regeneration - Composite scaffold enables cranial bone reconstruction without usual fixation material
Breast Cancer - Power3 Medical to focus early-detection breast cancer tests on blood serum
Business & Finance - Grifols closes out 2005 with a 15% increase in sales
Business Update - Biotest increases its market share worldwide, announces ambitious targets for 2006
Cancer Immunotherapy - Endothelial progenitor cells offer a way to target tumor angiogenesis
Cancer Therapy - Argentatin B derivatives developed as growth inhibitors of human cancer cells
Cancer Therapy - Proliferating cells should be targeted in cancer therapy
Cancer Therapy - Recent findings in cancer therapy described
Cardiac Hypertrophy - Cardiac hypertrophy and myelo-lymphoproliferative disorders are caused by gene haploinsufficiency
Cardiovascular Disease - Preclinical data show Samaritan's cardiovascular drug reduces cholesterol
Cardiovascular Research - High good cholesterol trumps low bad cholesterol for heart protection
Childhood Cancer - Childhood cancer survival prognostic factors identified
Clinical Trials - Phase 2 data show antiviral drug maribavir significantly reduces CMV reactivation in transplants
Cornea Transplantation - Corneal allograft rejection differentially involves CD8+ and CD8- T lymphocytes
Critical Care Medicine - Volume expansion outcome may be altered by adrenergic drugs
Diabetes Complications - InsR signaling in diabetes-impaired wounds is sensitive to inflammatory conditions
Diabetes Monitoring - FDA approval of continuous glucose sensor accelerates development of artificial pancreas
Diabetes Monitoring - FDA issues clearance for AgaMatrix's high-accuracy blood glucose monitor
Diabetes Research - Odd-looking pig is the focus of research into diabetes, infertility, and heart disease
Diagnostics - Low serotonin levels in plasma accurately measured by novel HPLC assay
Diagnostics - PCR-ELISA and real-time PCR adequately sensitive for CMV DNA quantitation after HSCT
Diagnostics - Plasma gelsolin predicts postoperative mortality
Diagnostics - Polymedco introduces CLIA waived assays on automated dry chemistry analyzer
Diagnostics - Proteomic screening leads to early detection of acute GVHD after stem cell transplantation
Diagnostics - Single drop of blood may help millions avoid dementia, anemia
Diagnostics - St. Jude develops follow-up test to identify children with acute lymphoblastic leukemia
Diet & Nutrition - Long-term lifestyle changes can lower rates of high blood pressure and risk of heart disease
Diet & Nutrition - Vitamin C measures in bloodstream correlate with body fat percentage
Drug Safety - Clinical relevance of statin-clopidogrel interaction needs further clarification
Ebola Virus - Ebola virus amplification is inhibited by VP35 knockdown
Embryonic Stem Cells - ESC-derived hematopoietic cells engraft primary and secondary fetal recipients
Finance - Chemokine Therapeutics closes additional $1.06 million private placement
Finance - Cleveland Clinic receives $13.5 million grant from the National Institutes of Health
Heart Transplantation - Diastolic dysfunction in human cardiac allografts is related to reduced SERCA2a gene expression
Hematology - Cambrix announces availability of Poietics normal peripheral blood leukopaks
Hematology - In cardiac surgery patients, peri-operative hemoglobin may mislead as indicator for transfusion
Hematology - Link between venous thrombo-embolism risk and ximelagatran treatment is not supported by study
Hematopoiesis - Peroxide-sensitive regulatory mechanisms play important role in controlling hematopoiesis
Hematopoiesis - Primitive hematopoietic cells give rise to daughter cells adopting different cell fates
Hepatitis B Virus - Recent findings in hepatitis B virus provide new insights
Hepatitis B Virus - Research in hepatitis B virus provides new insights
Hepatitis C Virus - Hepatitis C virus RNA negativity occurs among HCV-seropositive blood donors
Hypertension - Lack of sleep linked to increased risk of high blood pressure
Inflammatory Bowel Disease - Antihuman CD48 antibody treatment may represent a novel therapy for IBD patients
Intrahepatic Cholangiocarcinoma - ICC cancer cells originate from hepatic stem cells with hidden multidifferentiation potential
Kidney Disease - In end-stage renal disease, mitral E/Ea ratio predicts mortality
Leukemia - Acute myeloid leukemia patients prognosticated by BAALC expression
Leukemia - FLT3 D324N variant may be associated with a predisposition to different leukemia subtypes
Leukemia - Findings describe new data in leukemia research
Leukemia - Karyotypes of patients with adult acute myeloid leukemia analyzed in demographic study
Leukemia - Leukemia might be linked to CYP2D6, CYP1A1, CYP2E1, GSTT1, and GSTM1 genes
Leukemia - Leukemia progression inhibited by virgin olive oil phenols
Leukemia - Link between leukemia prognosis and multidrug resistance-related proteins studied
Leukemia - New findings in leukemia described
Leukemia - Quest Diagnostics launches tests to assess status of leukemia and lymphoma in using blood plasma
Leukemia - Recent findings in leukemia described
Liver Cancer - Hepatocellular cancer outcome improved with living-donor liver transplantation
Liver Cancer - Hepatocellular carcinoma outcome after lipiodol chemoembolization assessed
Liver Cancer - Researchers publish new studies and findings in the area of liver cancer
Liver Transplantation - Despite medical advances, children wait longer to receive a liver transplant than a decade ago
Liver Transplantation - Study predicts successful outcomes in living-donor liver transplants
Lymphoma - Lymphoma response to methotrexate might be affected by reduced folate carrier 1 polymorphisms
Market Analysis - Rising cholesterol levels could create welfare crisis in Europe by 2020, report concludes
Myeloma - Multiple myeloma treatment results interpreted by patient-reported outcomes
Neurogenesis - Abnormal NSC REST/NRSF and Myc expression causes cerebellar tumors by blocking neurogenesis
Neurogenesis - Astrocytes promote neurogenesis from oligodendrocyte precursor cells
Neurogenesis - Chondroitin sulfate proteoglycans are involved in neural stem cell proliferation
Neurogenesis - Long-term neurogenesis impairment is not a general feature of chronic epilepsy
Obesity Complications - Increased microparticle levels may account for high thrombotic complication risk in obese
Oncology - Researchers' work adds to oncology body of knowledge
Organ Donation Registry - California marks first year of Donate Life California, sets national record
Pancreatic Cancer - Pancreatic cancer diagnosis via RT-PCR for alpha4GnT shows promise
Parkinson Disease - 6-OHDA-induced damage increases viability of transplanted MSCs in Parkinson disease
Pediatric Cancer - Pediatric cancer patients experience endothelial injury caused by anthracyclines
Personnel - Stem Cell Therapeutics announces resignation of director Donald McCaffrey from board
Personnel - SunTech Medical adds Danielle McCulloch as product manager of stress blood pressure systems
Progenitor Cells - Progenitor cell differentiation and beta-catenin turnover is controlled by Cdc42
Pulmonary Arterial Hypertension - PR Pharmaceuticals initiates phase I study of treatment for pulmonary arterial hypertension
Sepsis - Masimo announces U.S. FDA clearance of Masimo Rainbow SET Rad-57cm
Sickle Cell Anemia - Sickle cell anemia patients may benefit from aged garlic extract
Skin Substitute - Hyperproliferative or activated phenotype in skin substitutes similar to wounded native skin
Stem Cell Research - Bone marrow cells can produce pulmonary epithelial cells
Stem Cell Research - Buffy coat preparation is a convenient source of progenitors for mature mast cell culture
Stem Cell Research - Cell selection based on ALDH activity and CD133 expression isolates long-term reconstituting HSCs
Stem Cell Research - Embryonic stem cell lines generated with diploid and triploid karyotypes
Stem Cell Research - Fibulin-2 is important for smooth muscle cell migration
Stem Cell Research - Hematopoietic stem cells trigger repair functions in eye disease models
Stem Cell Research - Nurr1 and Pitx3 cooperatively promote terminal maturation to midbrain dopamine neuron phenotype
Stem Cell Research - Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion
Stem Cell Research - RabGEF1 regulates SCF/c-Kit-mediated signaling events and biological responses in mast cells
Stem Cell Research - Rapidly self-renewing marrow stromal cell subset engrafts into nonhematopoietic tissues
Stem Cell Research - Tissue fibroblasts are derived from hematopoietic stem cells
Stem Cell Transplantation - Cultured BMCs differentiated into liver cell lineage are cell transplantation source
Stem Cell Transplantation - Cytogenetic response to prior IFN treatment predicts survival after AHSCT in CML
Stem Cell Transplantation - Exogenous erythropoietin protects grafted dopamine neurons in Parkinson disease
Stem Cell Transplantation - Neonatal hematopoietic stem cell transplantation cures osteopetrosis
Stem Cell Transplantation - Spermatogonial SCT developed to preserve and propagate male germ-plasm from valuable animals
Stroke - Research add new data to stroke body of knowledge
T Cells - T cells activated within the transplanted liver are completely differentiated
Tissue Engineering - Bioactive glasses support growth and maturation of primary osteoblasts
Tissue Engineering - CD31-CD45- side population cells participate in muscle regeneration
Tissue Engineering - Composite implant transformed into vascularized pedicled bone flap for hemi-mandible repair
Tissue Engineering - Demineralized bone matrix gelatin scaffold developed for osteochondral tissue engineering
Tissue Engineering - Extracellular matrix and fluid shear stress synergistically enhance 3D osteogenesis
Tissue Engineering - Findings in tissue engineering provide new insights
Tissue Engineering - PGA/chitin blend nanofibers are a candidate for tissue engineering scaffolds
Tissue Engineering - Vascular grafts cultured in a bioreactor characterized
Tissue Regeneration - Regulating activation of transplanted cells controls tissue regeneration
Transplant Medicine - Pancreatic islets develop lymphatic vessels after transplantation
Transplant Medicine - VCU medical center team implants first total artificial heart on East Coast
Tumor Biomarker - Nestin is marker for odontogenic ectomesenchyme and odontoblasts in odontogenic tumors
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