Tissue Engineering
Cell-cell competition replaces functional organ tissue under nonselective conditions
Published in Blood Weekly, April 27th, 2006
"A critical property of stem cells is their ability to repopulate an organ or tissue under nonselective conditions. The aims of this study were to determine whether we could obtain reproducible, high levels of liver repopulation by transplanted fetal liver stem/progenitor cells in normal adult liver and the mechanism by which liver replacement occurred.
"Wild-type (dipeptidyl peptidase IV [DPPIV+]) embryonic day (ED) 14 fetal liver cells underwent transplantation into DPPIV-mutant F344 rats to follow the fate and differentiation of transplanted cells," investigators...
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Source: Blood Weekly (2006-04-27)
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