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Intrahepatic Cholangiocarcinoma

ICC cancer cells originate from hepatic stem cells with hidden multidifferentiation potential

Published in Blood Weekly, April 27th, 2006

Intrahepatic cholangiocarcinoma cancer cells originate from hepatic stem cells with hidden multidifferentiation potential.

According to recent research published in the journal Pathology Research and Practice, "In general, intrahepatic cholangiocarcinoma (ICC) is not related to liver cirrhosis. However, a few cases have been reported in which ICC was accompanied by severe liver fibrosis."

"Intrahepatic cholangiocarcinoma cancer cells originate from hepatic precursor cells with hidden multidifferentiation potential. Some researchers have proposed that hepatocellular and cholangiocellular (HC-CC) carcinoma, an intermediate mixed phenotype...

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