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Stem Cell Transplantation

Ideal body weight should be used to calculate stem cell transplant cell dose

Published in Blood Weekly, May 4th, 2006

Ideal body weight should be used instead of actual body weight to calculate stem cell transplantation cell dose.

According to a study from the United States, "Whether the CD34+ and CD3+ cell doses in allogeneic HSCT should be estimated using actual (ABW) or ideal (IBW) body weight has never been definitively determined. We have shown that CD34+ cell doses based upon IBW are better predictive of engraftment after autologous and allogeneic HSCT."

"Sixty-three patients undergoing reduced-intensity HSCT after a uniform preparative regimen were evaluated to determine the effect of cell dose. ABW and IBW were 45-147 kg (median 79) and 52-85 kg (median 67)...

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