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Blood Banking

Flow cytometry quantifies nucleated red blood cells in umbilical cord blood units

Published in Blood Weekly, May 4th, 2006

Flow cytometry quantifies nucleated red blood cells in umbilical cord blood units more accurately than total nucleated cell analysis.

According to recent research from France, "Cord blood (CB) represents an alternate source of stem cells in transplantation. Nucleated red blood cells (NRBCs) are a physiological subset of CB population.

"Although it is important to have an accurate estimate of CD34+ cell number, NRBCs could compromise white blood cell count and interfere with CD34+ cell quantification."

"A total of 826 CB units were analyzed for total nucleated cells (TNCs), NRBCs, and CD34+ cells by flow cytometry. NRBCs were also...

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