Myelodysplasia Prognostic Markers
Immature hematopoietic progenitor cells CD34+/CD38(Dim) increased in myelodysplasia
Published in Blood Weekly, May 11th, 2006
"Myelodysplastic syndromes (MDS) are clonal disorders affecting hematopoietic progenitor cells (HPC). Despite the relevance of clonal CD34+ cells in developing MDS, only few studies analyze the phenotype of this cell population," scientists in Argentina report.
According to M.B. Monreal and colleagues at the Foundation to Fight Leukemia & Centro de Investigation in Buenos Aires, "The aim of this study was to evaluate phenotypic changes on HPC in MDS that could reflect abnormalities in the differentiation process of stem cells.
"We analyzed the...
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Source: Blood Weekly (2006-05-11)
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