Published in Blood Weekly, May 11th, 2006
"TNF-alpha mediated apoptosis of the hematopoietic cells has been thought to contribute to the ineffective hematopoiesis observed in MDS. The combination of pentoxifylline (P) and ciprofloxacin (C) has been shown to reduce the serum levels of TNF-alpha, and an earlier trial of P and C with dexamethasone (D) provided good palliation for patients with MDS," investigators in South Korea reported.
"The purpose of this study is to assess the hematologic response to PCD therapy for patients suffering with MDS," explained M.K. Kim and colleagues, Yeungnam University. "Twenty...
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