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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . May 25th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Blood Banking - Whole-blood leukoreduction filters are a source for cryopreserved cells

Blood Banking - Whole-blood storage time affects the number of white cells and platelets

Cardiovascular Research - Simple formula predicts blood needs in heart surgery

Renal Regeneration - Intrarenal cells are the main source for renal regeneration

Stem Cell Transplantation - Early allogeneic hematopoietic stem cell transplant beneficial in inherited disorders

Alzheimer Disease - Blood-derived microglia prevent or eliminate amyloid deposits in Alzheimer disease

Anemia - Seasonal childhood anemia in West Africa is associated with the haptoglobin 2-2 genotype

Angina - Refractory myocardial angina responds to percutaneous delivery of autologous bone marrow

Angiology - High glucose levels enhance platelet activation through multiple mechanisms

Angiology - Research from Greece, the United Kingdom and the United States add new data to angiology body of knowledge

Apoptosis - Studies from Scotland, the People's Republic of China and Japan describe new findings in apoptosis research

Artificial Liver - HepaLife's artificial liver cell research passes critical human plasma milestone

Atherosclerosis - Glucose control can reduce atherosclerosis risk in post-transplant diabetes mellitus

Atherosclerosis - Studies from the United Kingdom and United States advance knowledge in atherosclerosis research

Awards - HemoSense receives ABCO Fast Track - Vendor Award

Biomedical Engineering - Reports from Singapore, Italy and the United States describe recent advances in biomedical engineering research

Bone Marrow Cell Transfer - After acute MI, intracoronary bone marrow cell transfer improves diastolic function

Bone Marrow Cell Transfer - For severe chronic ischemic HF, cell therapy may improve cardiac deformation, mitral regurgitation

Brain Damage - G-CSF and SCF injection exacerbates excitotoxic brain injury in the newborn

Business Update - Karo Bio announces milestone payment from Wyeth for drug candidate to treat atherosclerosis

Business Update - Seattle Genetics, Laureate sign agreement to manufacture monoclonal antibody drug candidates

Cancer Gene Therapy - Mesenchymal progenitor cells deliver oncolytic adenoviruses

Cancer Therapy - Advanced cancer inpatients benefited from low molecular weight heparin

Cancer Therapy - Circulating endothelial and progenitor cells may function as biomarkers for antiangiogenic therapy

Cancer Therapy - Human leukemic cells are affected by a synthetic triterpenoid

Cancer Treatment - Data from Japan and the United States advance knowledge in cancer treatment research

Cancer Treatment - Data from the United States, Italy and Germany advance knowledge in cancer treatment research

Cancer Treatment - Researchers from Italy and Turkey publish new studies and findings in the area of cancer treatment

Cardiology - ADAMTS13 metalloprotease displays systemic antithrombotic effects

Cardiology - Heart valve recellularization can be compromised

Cell Biology - Data from the NORTH Ireland, Netherlands and Japan advance knowledge in cell biology research

Cell Biology - Studies from the United States, Germany and United Kingdom advance knowledge in cell biology research

Chemotherapy Adverse Reaction - Etoposide induces chromosomal abnormalities in spermatocytes and stem cell spermatogonia

Chlamydia Pneumoniae - Diabetes development promotes Chlamydia pneumoniae dissemination from lung to peripheral blood

Chronic Myeloid Leukemia - New chronic myeloid leukemia staging system proposed

Clinical Trials - Lipid Sciences gets approval from MedStar IRB to begin human trial of delipidation system

Collaborations - Dade Behring grants rights to American Diagnostica for use of factor VII-activating protease

Colon Cancer - Reports from Israel, the United States and Finland add new data to colon cancer research

Cord Blood - Studies from the United States and Japan describe new findings in cord blood research

Diabetes & Immunology - CD4+CD25+ regulatory T cells inhibit islet immune response and promote islet engraftment

Diabetes Complications - Methicillin-resistant Staphylococcus aureus infection enhanced inflammation and coagulation

Diabetes Therapy - Farnesoid X receptor activation improves lipid metabolism in combined hyperlipidemic hamsters

Diabetes Therapy - Pancreas versus islet transplantation in diabetes mellitus compared

Disease - Findings from the United States and Denmark advance knowledge in disease research

Disease Associations - For cardiovascular and kidney disease, treatment benefit of erythropoietin remains uncertain

Drug Development - Novartis' NDA for high blood pressure treatment accepted for review by U.S. FDA

Embryonic Stem Cell Research - Embryonic stem cell LRH-1 expression directed by mlrh-1 variant and promoter

Epstein-Barr Virus & Nephropathy - Systemic Epstein-Barr virus infection associated with membranous nephropathy in children

Facilities - Tianjin development area opens first Umbilical Cord Mesenchymal Stem Cell Bank in China

Gastric Cancer - Gastric cancer expression of hiwi gene linked to cell proliferation

Gastrointestinal Syndrome - Selective irradiation of vascular endothelium has no effect on intestinal crypt SC survival

Genetics & Genomics - NANOGP8 is a retrogene expressed in cancers

Genetics & Genomics - Osteoblast gene expression is modulated by a thrombin-coated biphasic calcium phosphate ceramic

HIV/AIDS Cognition - Caudate blood flow and volume reduced in neurocognitively impaired HIV/AIDS patients

HIV/AIDS Research - Liver transplants can be successful in HIV patients with Hepatitis B

Hair Studies - Wnt-10b secreted from lymphocytes promotes skin epithelial cell differentiation

Hematology - After cardiac surgery, hemostasis impaired by gelatin and hydroxyethyl starch, but not albumin

Hematology - Antiplatelet plus moderate intensity anticoagulant therapy effective in mitral stenosis patients

Hematology - Excessive bleeding in cardiac surgery associated with a doubled risk for excessive bleeding in second surgery

Hematology - Long-term anticoagulant therapy in patients with coronary artery disease reviewed

Hematology - New bleeding risk scheme, HEMORR2 HAGES, quantifies hemorrhage risk in antithrombotic therapy

Hepatitis B Virus - Hepatitis B virus is treatable prophylactically after liver transplantation

Hepatitis C Virus - Findings from Israel, Italy and Spain in hepatitis C virus provide new insights

Hepatitis C Virus - HCV in hemodialysis patients is linked to decreased plasma oxidative load

Hepatitis C Virus - Hepatitis C virus infection influences glomerulonephritis in renal allografts

Hepatitis C Virus - Hepatitis C virus RNA-dependent RNA polymerase inhibitors identified

Hepatitis C Virus - Research from Canada and Japan in hepatitis C virus provides new insights

Imaging - Neovascularities photoacoustically monitored in grafted skin

Imaging - Research from Germany, Australia and Italy add new data to imaging body of knowledge

Immunotherapy - HSP72 surface expression facilitates gamma delta T cell-mediated killing

Infant Leukemia - Low-dose etoposide induces mixed lineage leukemia rearrangement in fetal stem cells

Leukemia - Drug-resistant leukemia treated with 3'-azido disaccharide analogues of daunorubicin

Leukemia - Leukemia initial response to chemotherapy predicted event-free survival

Leukemia - Leukemia might be associated with low p53 expression

Leukemia - Leukemia poor prognosis linked to decreased ASPP1 gene promoter expression

Leukemia - Leukemia was treated by cytarabine in combination with 7-hydroxystaurosporine

Leukemia - Link between leukemia risk and methylenetetrahydrofolate reductase examined

Leukemia - New data from Japan, Scotland and Italy lluminates research in leukemia

Leukemia - Recent findings in leukemia described by researchers from Japan and the United States

Leukemia - Recent studies from the United Kingdom, United States and Greece add new data to leukemia research

Leukemia - Research from the United States and France in leukemia provides new insights

Leukemia - Researchers from Hungary, Greece and Germany publish new studies and findings in the area of leukemia

Leukemia - Researchers from Italy and Japan report details of new studies and findings in the area of leukemia

Leukemia - Researchers from the United States and Italy detail new studies and findings in the area of leukemia

Leukemia - Researchers' findings from Germany, the United States and Taiwan advance leukemia research

Leukemia - Studies from Germany, the United States and India add new findings to leukemia body of knowledge

Lipids - Reports from Japan, Lebanon and Italy describe recent advances in lipids research

Liver Cancer - Research from the United States and Germany in liver cancer provides new insights

Liver Disease - Hepatitis B- and C-related liver cirrhosis may involve similar roles for oval cells

Lung Cancer - Reduced lung cancer survival linked to increased pre-operative erythropoietin concentration

Lymphoma - Cutaneous T cell lymphoma progression linked to skin-derived interleukin-7

Lymphoma - Researchers from Germany and the United Kingdom publish new studies and findings in the area of lymphoma

Melanoma Vaccine - Stage IV melanoma survival improved by metastatic disease resection plus peptide vaccine

Mergers & Acquisitions - Wyndgate Technologies sells electronic blood bank system to St. John's Medical Center

Myocardial Infarction - During acute phase of MI, markers of thrombin generation transiently increase in patients with VF

Neurogenesis - Retinoic acid required early during adult neurogenesis in dentate gyrus

Neurology - New data from the United States, United Kingdom and Sweden lluminates research in neurology

Neurology - Research from the United States and Portugal in neurology provides new insights

Oncology - Findings from Germany, the South Korea and Cyprus describe new data in oncology research

Oncology - Research from Japan and Mexico in oncology provides new insights

Ophthalmology - Researchers from Spain, the United States and Israel report details of new studies and findings in the area of ophthalmology

Organ Transplant - Prograf now approved for prophylaxis use in heart transplantation across Europe

Patents - Rockwell Medical receives European patent for proprietary iron-delivery technology

Platelet Aggregation - Inspire begins phase II clinical trial of platelet aggregation inhibitor

Prion Research - Cultured neurospheres expressing cellular prion protein can be infected with prions

Product Licensing - Health Canada issues license to market handheld autologous thrombin processing device

Product Licensing - Primagen expands into cardiovascular field with CD133 diagnostic biomarker technology license

Pulmonary Hypertension - Predix completes PRX-08066 phase Ib trial for pulmonary hypertension

Spinal Cord Injury - Delayed adult neural precursor cell transplant promotes remyelination after spine injury

Statins - In CAD, postprandial pro-inflammatory, pro-coagulant changes can be modified by rosuvastatin

Stem Cell Research - Neural-like stem cells depend on previous long-term culture conditions

Stem Cell Research - Stem cell leukemia expressed in bone primordia during embryonic development

Stem Cell Research - Transcription factor MEF/ELF4 regulates quiescence of primitive hematopoietic cells

Stem Cell Research - Trophoblast stem cell survival controlled by Shp2/SFK/Ras/Erk signaling pathway

Stem Cell Transplantation - IL-6/soluble IL-6 receptor fusion protein increases ESC-derived oligodendrocyte myelination

Stem Cell Transplantation - Skeletal myoblast transplantation in MI patients improves myocardial function, viability, perfusion

Surgical Technology - Enrollment completed for trial of embolic protection system in carotid stenting procedures

Surgical Technology - U.S. FDA grants 510(k) clearance for Kensey Nash's thrombectomy catheter system

Tissue Engineering - Collagen matrices support chondrogenic differentiation

Tissue Engineering - Matrix-guided mesenchymal stem cells attracted to cartilage defect

Tissue Engineering - Mesenchymal type cells in dental papilla expanded/utilized for bone tissue engineering

Tissue Engineering - Viable pulmonary arteries engineered for surgical correction of congenital heart defects

Transplant Medicine - Late allograft failure could be caused by cumulative damage to the kidney

Transplant Medicine - Primary pediatric heart transplantation costs within accepted range of cost-effectiveness

Transplant Medicine - Submandibular gland allotransplantation is accomplished in a miniature swine model

Transplantation Biology - Renal allograft avascular osteonecrosis involves multiple factors

Transplantation Biology - Risk factors identified for diabetes mellitus in renal transplant recipients

Transplants - Recent studies from Turkey, Germany and Japan add new data to transplants research

Transplants - Reports from Japan, Sweden and Brazil add new data to transplants research

Transplants - Researchers from the United States describe findings in transplants studies

Transplants - Researchers' data from Germany, Iran and the United States advance transplants research

Transplants - Researchers' work from the United States and Spain adds to transplants body of knowledge

Transplants - Studies from France, Germany and the United States describe new findings in transplants research

Umbilical Cord Blood - Umbilical cord blood-related CD34+ cell levels variable when determined by flow cytometry

Virology - Dengue virus resistance engineered in genetically modified Aedes aegypti

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