Virology
Flavivirus RNA replication is inhibited by a triaryl pyrazoline compound
Published in Blood Weekly, June 8th, 2006
"Triaryl pyrazoline {[5-(4-chloro-phenyl)-3-thiophen-2-yl-4,5-dihydro-pyrazol-1-yl]-phenyl-methanone} inhibits flavivirus infection in cell culture. The inhibitor was identified through high-throughput screening of a compound library using a luciferase-expressing West Nile (WN) virus infection assay," wrote F. Puigbasagoiti and colleagues, New York State Department of Health.
"The compound inhibited an epidemic strain of WN virus without detectable cytotoxicity (a 50% effective concentration of 28 mcM and a compound...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Blood Weekly
Source: Blood Weekly (2006-06-08)
More Articles from Blood Weekly
- Angiology
Vascular walls are reservoirs for progenitor cells that propel postnatal vasculogenesis - Bioartificial Liver
Cold storage prior to culture or therapy prolongs bioartificial liver transportation time - Blood Safety
Transfusion-transmitted Klebsiella pneumoniae fatalities in U.S. are reported - Blood Vessel Tissue Engineering
Chitosan-derived sandwich tubular scaffold feasible for blood vessel tissue engineering - Stem Cell Research
Data supports importance of family umbilical cord blood banking - Angiology
Carotid angioplasty with a novel stent implant effective in an experimental model - More from this issue of Blood Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
