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Blood Vessel Tissue Engineering

Chitosan-derived sandwich tubular scaffold feasible for blood vessel tissue engineering

Published in Blood Weekly, June 8th, 2006

A chitosan-derived sandwich tubular scaffold is feasible for blood vessel tissue engineering.

"Many materials have been investigated in blood vessel tissue engineering, such as PGA, PLGA, P4HB. However, chitosan is not mentioned in the arena. This study aimed to develop a chitosan-based tubular scaffold and examine its feasibility of being applied in this field," scientists in the People's Republic of China report.

According to L. Zhang and colleagues at Tsing Hua University in Beijing, "Briefly, a knitted chitosan tube was dipped into chitosan solution (2%, w/v) and dried, then its inner and outer Surface was mantled with a layer of chitosan/gelatin...

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