Published in Blood Weekly, June 22nd, 2006
Study 1: At 1 year after transplantation, morphologic changes compatible with the early stage of graft vasculopathy are accompanied by hypersensitivity to serotonin unresponsive to vitamin C, despite a relatively preserved endothelial function.
Investigators in Belgium report, "Coronary hypersensitivity to serotonin promotes platelet aggregation, entailing the progression of the atherosclerotic process. This abnormality is a common finding in cardiac transplant recipients and may be triggered by reactive oxygen species, which plays a main role in the...
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