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Malaria Vaccine

 Plasmodium falciparum MSP-1 asexual blood stage vaccine is safe and immunogenic

Published in Blood Weekly, June 22nd, 2006

The Plasmodium falciparum MSP-1 asexual blood stage vaccine is immunogenic.

"We report the first safety and immunogenicity trial of the Plasmodium falciparum malaria blood stage vaccine candidate, FMP1/AS02A consisting of the FMP1 antigen, an Escherichia coli-expressed His-tagged fusion protein from the 42 kDa C-terminal fragment from the 3D7 clone of the merozoite surface protein 1 formulated in the AS02A adjuvant," scientists in the United states wrote.

C.F. Ockenhouse and colleagues at Walter Reed Army Institute of Research in Silver Spring conducted an open label, "prospective, single-center Phase 1 dose escalation trial of...

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